Could DTI Unlock the Mystery of Subjective Tinnitus: It's Time for Parameters That Go A Little Out of the Routine.

IF 0.6 Q4 SURGERY

Indian Journal of Otolaryngology and Head and Neck Surgery Pub Date : 2024-12-01 Epub Date: 2024-08-28 DOI:10.1007/s12070-024-04963-7

Eren Yilmaz, Duzgun Yildirim, Deniz Esin Tekcan Sanli, Pinar Elpen, Filiz Gosterisli Tuzuner, Neslihan Gokmen Inan, Ahmet Sirin, Mustafa Yagimli, Hakan Tozan, Ahmet Necati Sanli, Sedat Giray Kandemirli

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引用次数: 0

Abstract

In this study, it was aimed to assess the microstructural changes in the main central auditory pathway in cases with subjective tinnitus. In total, 101 subjects (52 cases with bilateral subjective non-pulsatile tinnitus and 49 healthy cases as the control group) were included in the study. Participants underwent pure tone audiogram and Diffusion Tensor Imaging-Magnetic Resonance Imaging (DTI-MRI) examination with a 3 Tesla MRI device. The number of tracts, tract length, volume, and quantitative anisotropy (QA) and normalized quantitative anisotropy' (nQA) values were calculated by plotting cochleocortical pathways from the cochlear nerve to ipsilateral and contralateral Heschl's gyrus (HG). In pure tone audiometry, the control group had lower hearing thresholds than cases with tinnitus. Fibres and nQA values from the right cochlear nerve to the right HG were significantly lower in the tinnitus group than in the control group. Cochlear nuclei voxel counts were significantly decreased in the tinnitus group. Both cochlear nucleus volumes were higher in the tinnitus group than in the control group. nQA values in both cochlear nuclei were decreased in the tinnitus group. This study showed that the most commonly affected part in subjective non-pulsatile tinnitus cases is the cochlear nucleus. Therefore, the cochlear nucleus should be evaluated more carefully in cases presenting with subjective tinnitus.

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DTI 能否揭开主观性耳鸣之谜？是时候让参数跳出常规了

本研究旨在评估主观性耳鸣患者的主要中央听觉通路的微结构变化。研究共纳入 101 名受试者（52 名双侧主观性非脉冲性耳鸣病例和 49 名健康病例作为对照组）。受试者接受了纯音听力图检查和弥散张量成像-磁共振成像（DTI-MRI）检查。通过绘制从耳蜗神经到同侧和对侧赫氏回（HG）的耳蜗皮质通路图，计算了通路数量、通路长度、体积、定量各向异性（QA）和归一化定量各向异性（nQA）值。在纯音测听中，对照组的听阈低于耳鸣病例。耳鸣组从右耳蜗神经到右侧 HG 的纤维和 nQA 值明显低于对照组。耳鸣组的耳蜗核体素数明显减少。耳鸣组两个耳蜗核的体积均高于对照组。这项研究表明，主观性非脉冲性耳鸣病例中最常受影响的部位是耳蜗核。因此，在出现主观性耳鸣时，应更仔细地评估耳蜗核。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Indian Journal of Otolaryngology and Head and Neck Surgery Medicine-Otorhinolaryngology

CiteScore

0.80

自引率

0.00%

发文量

226

审稿时长

6-12 weeks

期刊介绍： Indian Journal of Otolaryngology and Head & Neck Surgery was founded as Indian Journal of Otolaryngology in 1949 as a scientific Journal published by the Association of Otolaryngologists of India and was later rechristened as IJOHNS to incorporate the changes and progress. IJOHNS, undoubtedly one of the oldest Journals in India, is the official publication of the Association of Otolaryngologists of India and is about to publish it is 67th Volume in 2015. The Journal published quarterly accepts articles in general Oto-Rhino-Laryngology and various subspecialities such as Otology, Rhinology, Laryngology and Phonosurgery, Neurotology, Head and Neck Surgery etc. The Journal acts as a window to showcase and project the clinical and research work done by Otolaryngologists community in India and around the world. It is a continued source of useful clinical information with peer review by eminent Otolaryngologists of repute in their respective fields. The Journal accepts articles pertaining to clinical reports, Clinical studies, Research articles in basic and applied Otolaryngology, short Communications, Clinical records reporting unusual presentations or lesions and new surgical techniques. The journal acts as a catalyst and mirrors the Indian Otolaryngologist’s active interests and pursuits. The Journal also invites articles from senior and experienced authors on interesting topics in Otolaryngology and allied sciences from all over the world. The print version is distributed free to about 4000 members of Association of Otolaryngologists of India and the e-Journal shortly going to make its appearance on the Springer Board can be accessed by all the members. Association of Otolaryngologists of India and M/s Springer India group have come together to co-publish IJOHNS from January 2007 and this bondage is going to provide an impetus to the Journal in terms of international presence and global exposure.