A simple and highly selective chalcone fluorescent chemical sensor for the detection of tryptophane

IF 2.4 3区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Polyhedron Pub Date : 2024-11-13 DOI:10.1016/j.poly.2024.117303

Yuting Liu , Zixu Zhang , Dawei Yin , Yukai Huang , Ying Liu , Jinze Li , Ruilin Zheng

引用次数: 0

Abstract

In this study, 1-ferrocenyl-3-(2-hydroxyphenyl) allyl ketone (probe A) was synthesized using a solvent-free method in conjunction with solid-phase grinding and employed as a probe for the detection of tryptophan (Trp). The probe exhibits selective recognition of Trp as evidenced by UV–Vis and fluorescence spectra. In complex scenarios, the probe’s recognition of Trp remains unaffected by both the presence of interfering substances and the duration of exposure. A pH range of 8 to 12 is found to be optimal for the detection of Trp. Job’s curve analysis revealed that the binding ratio between the probe and Trp is 1:1. Based on the Benesi-Hildebrand equation, the binding constant for the interaction between probe A and Trp is calculated to be 1.5 × 10⁷ M⁻¹. The detection limit for Trp was determined to be 9.55 × 10⁻⁵ M. The sensing mechanism of the probe for Trp was elucidated through ¹H NMR and FT-IR analyses.

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用于检测色氨酸的简单、高选择性查尔酮荧光化学传感器

本研究采用固相研磨和无溶剂方法合成了 1-二茂铁基-3-（2-羟基苯基）烯丙基酮（探针 A），并将其用作检测色氨酸（Trp）的探针。紫外可见光谱和荧光光谱证明，该探针对 Trp 具有选择性识别能力。在复杂的情况下，探针对 Trp 的识别不受干扰物质存在和暴露时间长短的影响。检测 Trp 的最佳 pH 值范围为 8 至 12。约伯曲线分析表明，探针与 Trp 的结合率为 1:1。根据 Benesi-Hildebrand 方程计算，探针 A 与 Trp 之间的结合常数为 1.5 × 107 M-1。通过 1H NMR 和 FT-IR 分析，阐明了探针对 Trp 的感应机制。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Polyhedron 化学-晶体学

CiteScore

4.90

自引率

7.70%

发文量

515

审稿时长

2 months

期刊介绍： Polyhedron publishes original, fundamental, experimental and theoretical work of the highest quality in all the major areas of inorganic chemistry. This includes synthetic chemistry, coordination chemistry, organometallic chemistry, bioinorganic chemistry, and solid-state and materials chemistry. Papers should be significant pieces of work, and all new compounds must be appropriately characterized. The inclusion of single-crystal X-ray structural data is strongly encouraged, but papers reporting only the X-ray structure determination of a single compound will usually not be considered. Papers on solid-state or materials chemistry will be expected to have a significant molecular chemistry component (such as the synthesis and characterization of the molecular precursors and/or a systematic study of the use of different precursors or reaction conditions) or demonstrate a cutting-edge application (for example inorganic materials for energy applications). Papers dealing only with stability constants are not considered.