Wei Yang , Dan Zhou , Hui Peng , Huilin Jiang , Weifeng Chen
{"title":"The association between body temperature and 28-day mortality in sepsis patients: A retrospective observational study","authors":"Wei Yang , Dan Zhou , Hui Peng , Huilin Jiang , Weifeng Chen","doi":"10.1016/j.medine.2024.08.004","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><div>This study explored the association between body temperature and 28-day septic ICU hospital mortality.</div></div><div><h3>Design</h3><div>Retrospective cohort analysis.</div></div><div><h3>Setting</h3><div>208 ICUs in the United States.</div></div><div><h3>Patients or participants</h3><div>Sepsis patients from 2014–2015 eICU Collaborative Research Database.</div></div><div><h3>Interventions</h3><div>Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.</div></div><div><h3>Main variables of interest</h3><div>Body temperature, 28-day inpatient mortality.</div></div><div><h3>Results</h3><div>Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70–0.80, p < 0.0001).</div></div><div><h3>Conclusions</h3><div>Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.</div></div>","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":"49 4","pages":"Pages 205-215"},"PeriodicalIF":0.0000,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina intensiva","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2173572724002625","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective
This study explored the association between body temperature and 28-day septic ICU hospital mortality.
Design
Retrospective cohort analysis.
Setting
208 ICUs in the United States.
Patients or participants
Sepsis patients from 2014–2015 eICU Collaborative Research Database.
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