Wei Yang, Dan Zhou, Hui Peng, Huilin Jiang, Weifeng Chen
{"title":"The association between body temperature and 28-day mortality in sepsis patients: A retrospective observational study.","authors":"Wei Yang, Dan Zhou, Hui Peng, Huilin Jiang, Weifeng Chen","doi":"10.1016/j.medine.2024.08.004","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>This study explored the association between body temperature and 28-day septic ICU hospital mortality.</p><p><strong>Design: </strong>Retrospective cohort analysis.</p><p><strong>Setting: </strong>208 ICUs in the United States.</p><p><strong>Patients or participants: </strong>Sepsis patients from 2014-2015 eICU Collaborative Research Database.</p><p><strong>Interventions: </strong>Binary logistic regression models, Generalized Additive Model (GAM), Two-Piece Binary Logistic Regression Model.</p><p><strong>Main variables of interest: </strong>Body temperature, 28-day inpatient mortality.</p><p><strong>Results: </strong>Nonlinear relationship observed; hypothermia (≤36.67 ℃) associated with increased mortality (adjusted OR = 0.74, 95% CI: 0.70-0.80, p < 0.0001).</p><p><strong>Conclusions: </strong>Hypothermia in sepsis correlates with higher mortality; rewarming's potential benefit warrants further exploration.</p>","PeriodicalId":94139,"journal":{"name":"Medicina intensiva","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2024-11-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Medicina intensiva","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1016/j.medine.2024.08.004","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
Objective: This study explored the association between body temperature and 28-day septic ICU hospital mortality.
Design: Retrospective cohort analysis.
Setting: 208 ICUs in the United States.
Patients or participants: Sepsis patients from 2014-2015 eICU Collaborative Research Database.
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