Reaction Optimization Experiment for Undergraduate Capstone Organic Chemistry Laboratory Course.

IF 2.5 3区 教育学 Q2 CHEMISTRY, MULTIDISCIPLINARY
Journal of Chemical Education Pub Date : 2024-10-08 eCollection Date: 2024-11-12 DOI:10.1021/acs.jchemed.4c00030
Jayalakshmi Sridhar, Galina Goloverda
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引用次数: 0

Abstract

Molecular Structure and Organic Synthesis (MSOS) is an upper-division undergraduate (capstone) laboratory course for undergraduates majoring in chemistry at Xavier University of Louisiana (XULA). The course is designed for juniors and seniors and is based on self-regulated research and learning under limited instructor supervision. It includes a 2-step synthetic project, chosen by each student in the class from a list based on the Organic Synthesis periodical or actual faculty research and then carried out independently. In order to prepare students for their syntheses, we recently included a new project in the course syllabus focused on a reaction optimization that introduces the undergraduate students to the concepts of raising reaction yield, improving product purity, lessening the environmental impact of the reaction, and/or increasing its cost efficiency. A team of 2-3 students performs a preliminary experiment. A rerun by each individual team member incorporating his or her modifications follows this. The goal of this preparatory exercise is to enhance the students' soft skills, including teamwork, critical analysis of data, and scientific report preparation as well as develop a deeper understanding of the reaction mechanism to make calculated adjustments to reaction conditions for optimization.

本科生顶点有机化学实验课程的反应优化实验。
分子结构与有机合成(MSOS)是路易斯安那泽维尔大学(XULA)化学专业本科生的高年级(毕业设计)实验课程。该课程专为大三和大四学生设计,在有限的教师指导下进行自我调节的研究和学习。该课程包括两个步骤的合成项目,由班上每个学生根据《有机合成》期刊或教师的实际研究从列表中选择,然后独立完成。为了让学生为合成做好准备,我们最近在课程大纲中加入了一个新项目,该项目以反应优化为重点,向本科生介绍提高反应产率、提高产品纯度、减少反应对环境的影响和/或提高成本效益等概念。由 2-3 名学生组成的小组进行初步实验。随后,每个小组成员根据自己的修改意见重新进行实验。这一准备性练习的目的是提高学生的软技能,包括团队合作、数据批判性分析和科学报告的准备,以及加深对反应机理的理解,从而对反应条件进行计算调整,以实现优化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Journal of Chemical Education
Journal of Chemical Education 化学-化学综合
CiteScore
5.60
自引率
50.00%
发文量
465
审稿时长
6.5 months
期刊介绍: The Journal of Chemical Education is the official journal of the Division of Chemical Education of the American Chemical Society, co-published with the American Chemical Society Publications Division. Launched in 1924, the Journal of Chemical Education is the world’s premier chemical education journal. The Journal publishes peer-reviewed articles and related information as a resource to those in the field of chemical education and to those institutions that serve them. JCE typically addresses chemical content, activities, laboratory experiments, instructional methods, and pedagogies. The Journal serves as a means of communication among people across the world who are interested in the teaching and learning of chemistry. This includes instructors of chemistry from middle school through graduate school, professional staff who support these teaching activities, as well as some scientists in commerce, industry, and government.
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