{"title":"Reaction Optimization Experiment for Undergraduate Capstone Organic Chemistry Laboratory Course.","authors":"Jayalakshmi Sridhar, Galina Goloverda","doi":"10.1021/acs.jchemed.4c00030","DOIUrl":null,"url":null,"abstract":"<p><p>Molecular Structure and Organic Synthesis (MSOS) is an upper-division undergraduate (capstone) laboratory course for undergraduates majoring in chemistry at Xavier University of Louisiana (XULA). The course is designed for juniors and seniors and is based on self-regulated research and learning under limited instructor supervision. It includes a 2-step synthetic project, chosen by each student in the class from a list based on the Organic Synthesis periodical or actual faculty research and then carried out independently. In order to prepare students for their syntheses, we recently included a new project in the course syllabus focused on a reaction optimization that introduces the undergraduate students to the concepts of raising reaction yield, improving product purity, lessening the environmental impact of the reaction, and/or increasing its cost efficiency. A team of 2-3 students performs a preliminary experiment. A rerun by each individual team member incorporating his or her modifications follows this. The goal of this preparatory exercise is to enhance the students' soft skills, including teamwork, critical analysis of data, and scientific report preparation as well as develop a deeper understanding of the reaction mechanism to make calculated adjustments to reaction conditions for optimization.</p>","PeriodicalId":43,"journal":{"name":"Journal of Chemical Education","volume":"101 11","pages":"4680-4685"},"PeriodicalIF":2.5000,"publicationDate":"2024-10-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11562579/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Chemical Education","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1021/acs.jchemed.4c00030","RegionNum":3,"RegionCategory":"教育学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/12 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
引用次数: 0
Abstract
Molecular Structure and Organic Synthesis (MSOS) is an upper-division undergraduate (capstone) laboratory course for undergraduates majoring in chemistry at Xavier University of Louisiana (XULA). The course is designed for juniors and seniors and is based on self-regulated research and learning under limited instructor supervision. It includes a 2-step synthetic project, chosen by each student in the class from a list based on the Organic Synthesis periodical or actual faculty research and then carried out independently. In order to prepare students for their syntheses, we recently included a new project in the course syllabus focused on a reaction optimization that introduces the undergraduate students to the concepts of raising reaction yield, improving product purity, lessening the environmental impact of the reaction, and/or increasing its cost efficiency. A team of 2-3 students performs a preliminary experiment. A rerun by each individual team member incorporating his or her modifications follows this. The goal of this preparatory exercise is to enhance the students' soft skills, including teamwork, critical analysis of data, and scientific report preparation as well as develop a deeper understanding of the reaction mechanism to make calculated adjustments to reaction conditions for optimization.
期刊介绍:
The Journal of Chemical Education is the official journal of the Division of Chemical Education of the American Chemical Society, co-published with the American Chemical Society Publications Division. Launched in 1924, the Journal of Chemical Education is the world’s premier chemical education journal. The Journal publishes peer-reviewed articles and related information as a resource to those in the field of chemical education and to those institutions that serve them. JCE typically addresses chemical content, activities, laboratory experiments, instructional methods, and pedagogies. The Journal serves as a means of communication among people across the world who are interested in the teaching and learning of chemistry. This includes instructors of chemistry from middle school through graduate school, professional staff who support these teaching activities, as well as some scientists in commerce, industry, and government.