Missing appointments in Parkinson´s Disease: A longitudinal study on the pattern of attendance and its effects on motor and non-motor symptoms, quality of life and disability progression

IF 1.8 4区医学 Q3 CLINICAL NEUROLOGY

Clinical Neurology and Neurosurgery Pub Date : 2024-11-12 DOI:10.1016/j.clineuro.2024.108641

Marta Magriço , Bruna Meira , Marco Fernandes , Manuel Salavisa , João Pedro Marto , Raquel Barbosa , Paulo Bugalho

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引用次数: 0

Abstract

Background and purpose

Parkinson's Disease (PD) requires regular therapeutic adjustments and ongoing outpatient clinic follow-up. Nevertheless, the impact of appointment non-attendance on PD patients concerning the different symptomatic dimensions of the condition remains uncertain. We compared the level of attendance of PD and Essential Tremor (ET) patients and assessed the value of attendance variables as predictors of progression in cognition, motor dysfunction, affect, disability and health-related quality of life in PD.

Methods

The number of attended, no-shows and cancelled appointments of PD and ET patients were collected over 4 years. PD patients were assessed at baseline and 4 years later with the Non-Motor Symptoms Scale (NMSS), cognition (MoCA), disability (Schwab and England [S&E]), motor dysfunction (UPDRS-III), health-related quality of life measured with EQ-5D and hospital anxiety and depression scale (HADS). Linear regression (univariate) was used to test the correlation between the number of appointments (predictors) and absolute change in the NMSS, MoCA, S&E, UPDRS-III, EQ-5D and HADS.

Results

62 PD and 35 ET patients were assessed. PD patients attended more appointments (8,08 ± 3,13 vs 5,43 ± 2,09) and had a similar number of no-shows (0,39 ± 0,66 vs 0,46 ± 0,70) and cancelled (0,74 ± 0,88 vs 0,54 ±0,65) appointments than ET patients. In the univariate analysis there was a significant relation between the number of cancelled appointments and change in the S&E score (B=6375; p=0022).

Conclusion

Our findings suggest the number of cancelled appointments, but not no-shows, could be considered a predictor of disability progression in PD.

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帕金森病患者的失约：关于就诊模式及其对运动和非运动症状、生活质量和残疾进展影响的纵向研究。

背景和目的：帕金森病（Parkinson's Disease，PD）需要定期调整治疗方案并持续进行门诊随访。然而，就帕金森病的不同症状层面而言，不赴约对帕金森病患者的影响仍不确定。我们比较了帕金森病患者和重症震颤（ET）患者的出诊情况，并评估了出诊变量作为帕金森病认知、运动功能障碍、情感、残疾和健康相关生活质量进展预测因子的价值：收集了帕金森氏症和重症肢体瘫痪患者4年来的就诊次数、未就诊次数和取消就诊次数。对帕金森病患者进行基线和4年后的非运动症状量表（NMSS）、认知（MoCA）、残疾（Schwab and England [S&E]）、运动功能障碍（UPDRS-III）、健康相关生活质量（EQ-5D）和医院焦虑抑郁量表（HADS）评估。采用线性回归（单变量）检验预约次数（预测因素）与NMSS、MoCA、S&E、UPDRS-III、EQ-5D和HADS绝对变化之间的相关性：62 名帕金森氏症患者和 35 名急症患者接受了评估。与 ET 患者相比，PD 患者赴约次数更多（8,08 ± 3,13 vs 5,43 ± 2,09），未赴约次数（0,39 ± 0,66 vs 0,46 ± 0,70）和取消次数（0,74 ± 0,88 vs 0,54 ± 0,65）相似。在单变量分析中，取消预约次数与 S&E 评分变化之间存在显著关系（B=6375；P=0022）：我们的研究结果表明，取消预约次数（而非未赴约次数）可被视为预测帕金森病残疾进展的一个因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Clinical Neurology and Neurosurgery 医学-临床神经学

CiteScore

3.70

自引率

5.30%

发文量

358

审稿时长

46 days

期刊介绍： Clinical Neurology and Neurosurgery is devoted to publishing papers and reports on the clinical aspects of neurology and neurosurgery. It is an international forum for papers of high scientific standard that are of interest to Neurologists and Neurosurgeons world-wide.