BoneScore: A natural language processing algorithm to extract bone mineral density data from DXA scans.

IF 2.2 3区 医学 Q2 HEALTH CARE SCIENCES & SERVICES
Samah Fodeh, Rixin Wang, Terrence E Murphy, Farah Kidwai-Khan, Linda S Leo-Summers, Baylah Tessier-Sherman, Evelyn Hsieh, Julie A Womack
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引用次数: 0

Abstract

Objective: To develop and test an NLP algorithm that accurately detects the presence of information reported from DXA scans containing femoral neck T-scores of the patients scanned. Methods: A rule-based NLP algorithm that iteratively built a collection of regular expressions in testing data consisting of 889 snippets of text pulled from DXA reports. This was manually checked by clinical experts to determine the proportion of manually verified annotations that contained T-score information detected by this algorithm called 'BoneScore'. Testing of 30- and 50-word lengths on each side of the key term 'femoral' were pursued until achievement of adequate accuracy. A separate clinical validation regressed the extracted T-score values on five risk factors with established associations. Results: BoneScore built a set of 20 regular expressions that in concert with a width of 50 words on each side of the key term yielded an accuracy of 98% in the testing data. The extracted T-scores, when modeled with multivariable linear regression, consistently exhibited associations supported by the literature. Conclusion: BoneScore uses regular expressions to accurately extract annotations of T-score values of bone mineral density with a width of 50 words on each side of the key term. The extracted T-scores exhibit clinical face validity.

BoneScore:从 DXA 扫描中提取骨矿物质密度数据的自然语言处理算法。
目的开发并测试一种 NLP 算法,该算法可准确检测 DXA 扫描报告中是否存在包含被扫描患者股骨颈 T 值的信息。方法: 基于规则的 NLP 算法:采用基于规则的 NLP 算法,在从 DXA 报告中提取的 889 个文本片段组成的测试数据中迭代建立正则表达式集合。临床专家对此进行了人工检查,以确定经人工验证的注释中包含该算法检测到的 T 评分信息的比例,该算法称为 "BoneScore"。在关键术语 "股骨 "的两侧分别测试了 30 和 50 个字的长度,直到达到足够的准确性。另外还进行了临床验证,将提取的 T 评分值与五个已确定关联的风险因素进行回归。结果BoneScore 建立了一套 20 个正则表达式,配合关键字每边 50 个字的宽度,测试数据的准确率达到 98%。用多元线性回归建模时,提取的 T 值始终显示出文献支持的关联性。结论BoneScore 使用正则表达式准确提取了骨矿物质密度 T 分数值的注释,关键术语每边宽度为 50 个单词。提取的 T 值具有临床表面有效性。
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来源期刊
Health Informatics Journal
Health Informatics Journal HEALTH CARE SCIENCES & SERVICES-MEDICAL INFORMATICS
CiteScore
7.80
自引率
6.70%
发文量
80
审稿时长
6 months
期刊介绍: Health Informatics Journal is an international peer-reviewed journal. All papers submitted to Health Informatics Journal are subject to peer review by members of a carefully appointed editorial board. The journal operates a conventional single-blind reviewing policy in which the reviewer’s name is always concealed from the submitting author.
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