[Antiarrhythmic drugs will no longer be of importance in the treatment of atrial fibrillation in the future : Pros and cons].

Q4 Medicine
Andreas Metzner, Constanze Schmidt
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引用次数: 0

Abstract

An early rhythm stabilization is the primary focus of the current treatment of atrial fibrillation. Based on current studies catheter ablation of pulmonary vein isolation (PVI) is an established component in the treatment of atrial fibrillation. Therefore, in the management of affected patients this procedure should be offered at an early stage in addition to the holistic treatment approach with consistent treatment of cardiovascular risk factors and thromboembolism prophylaxis with anticoagulants. Substances with an antiarrhythmic effect can be included in a supportive role in the management of atrial fibrillation. Pharmacotherapy could also perspectively play an important role in the treatment of the underlying atrial cardiomyopathy of the phenotype of atrial fibrillation. An understanding of the atrial pathophysiology of individual patients with adapted selection of suitable treatment strategies of ablation up to pharmacotherapy is decisive for the successful antiarrhythmic outcome. The decision on the treatment strategy must always be individually made together with the affected patient. The advantages and disadvantages of both options must be explained in detail and pre-existing comorbidities and risk factors must be included. Additionally, the individual wishes of the patient must be taken into account.

[抗心律失常药物在未来治疗心房颤动中不再重要:利弊]。
尽早稳定心律是目前治疗心房颤动的首要重点。根据目前的研究,肺静脉隔离导管消融术(PVI)是治疗心房颤动的一个成熟组成部分。因此,在治疗受影响的患者时,除了采用整体治疗方法,坚持治疗心血管风险因素和使用抗凝剂预防血栓栓塞外,还应在早期阶段提供这种治疗方法。具有抗心律失常作用的药物可在心房颤动的治疗中发挥辅助作用。药物疗法在治疗心房颤动表型的潜在心房心肌病方面也可发挥重要作用。了解每位患者的心房病理生理学,并根据具体情况选择合适的治疗策略(从消融到药物治疗),对成功抗心律失常起着决定性作用。治疗策略的决定必须始终与患者共同作出。必须详细解释两种方案的优缺点,并将原有的合并症和风险因素考虑在内。此外,还必须考虑患者的个人意愿。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Herzschrittmachertherapie und Elektrophysiologie
Herzschrittmachertherapie und Elektrophysiologie Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.10
自引率
0.00%
发文量
76
期刊介绍: Mit wissenschaftlichen Original- und Übersichtsarbeiten, Berichten über moderne Operationstechniken und experimentelle Methoden ist die Zeitschrift Herzschrittmachertherapie + Elektrophysiologie ein Diskussionsforum für Themen wie: - Zelluläre Elektrophysiologie - Theoretische Elektrophysiologie - Klinische Elektrophysiologie - Angewandte Herzschrittmachertherapie - Bradykarde und tachykarde Herzrhythmusstörungen - Plötzlicher Herztod und Risikostratifikation - Elektrokardiographie - Elektromedizinische Technologie - Experimentelle und klinische Pharmakologie - Herzchirurgie bei Herzrhythmusstörungen Mitteilungen der Arbeitsgruppen Herzschrittmacher und Arrhythmie der Deutschen Gesellschaft für Kardiologie - Herz und Kreislaufforschung e.V. (DGK) sowie Stellungnahmen und praktische Hinweise runden das breite Spektrum dieser Zeitschrift ab. Interessensgebiete: Kardiologie, Herzschrittmachertherapie, Herzschrittmachertechnologie, klinische Elektrophysiologie
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