Impact of nutritional status in patients with metastatic spinal tumors who underwent palliative surgery.

IF 1.5 4区医学 Q3 ORTHOPEDICS

Journal of Orthopaedic Science Pub Date : 2024-11-08 DOI:10.1016/j.jos.2024.10.007

Masahiro Iinuma, Tsutomu Akazawa, Yoshiaki Torii, Jun Ueno, Atsuhiro Yoshida, Ken Tomochika, Takahiro Hideshima, Naoki Haraguchi, Hisateru Niki

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引用次数: 0

Abstract

Background: Preoperative nutritional status significantly affects postoperative outcomes in patients with metastatic spinal tumors. Understanding the relationship between nutritional status and survival rates can help optimize treatment strategies and improve patient outcomes.

Methods: This retrospective study was performed on 57 patients who underwent palliative surgery between May 2009 and April 2023. Various indicators of nutritional status including the Japanese-modified Glasgow Prognostic Score (JmGPS), C-reactive protein-to-albumin ratio (CAR), and prognostic nutrition index (PNI) were evaluated.

Results: Results showed that a lower JmGPS and CAR and a higher PNI were associated with a longer survival after surgery. Patients with a JmGPS score of 0 had a better postoperative performance status, higher likelihood of postoperative chemotherapy, and a greater median survival (>1 year). Further, CAR and PNI were predictive indicators of a better postoperative performance status and the implementation of chemotherapy.

Conclusion: Assessing preoperative nutritional status can predict survival and postoperative outcomes in patients with metastatic spinal tumors. The current findings underscore the importance of nutritional assessment in optimizing treatment strategies and improving outcomes.

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接受姑息手术的转移性脊柱肿瘤患者营养状况的影响。

背景：术前营养状况对转移性脊柱肿瘤患者的术后效果有很大影响。了解营养状况与生存率之间的关系有助于优化治疗策略，改善患者预后：这项回顾性研究针对 2009 年 5 月至 2023 年 4 月期间接受姑息手术的 57 名患者。方法：这项回顾性研究对2009年5月至2023年4月期间接受姑息手术的57名患者进行了评估，评估了各种营养状况指标，包括日本修订格拉斯哥预后评分（JmGPS）、C反应蛋白与白蛋白比值（CAR）和预后营养指数（PNI）：结果显示，JmGPS和CAR越低、PNI越高，术后生存期越长。JmGPS评分为0分的患者术后表现较好，术后化疗的可能性较高，中位生存期（>1年）较长。此外，CAR和PNI是预测术后表现状况和化疗实施情况的指标：结论：评估术前营养状况可预测转移性脊柱肿瘤患者的生存率和术后效果。目前的研究结果强调了营养评估在优化治疗策略和改善预后方面的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Orthopaedic Science 医学-整形外科

CiteScore

3.00

自引率

0.00%

发文量

290

审稿时长

90 days

期刊介绍： The Journal of Orthopaedic Science is the official peer-reviewed journal of the Japanese Orthopaedic Association. The journal publishes the latest researches and topical debates in all fields of clinical and experimental orthopaedics, including musculoskeletal medicine, sports medicine, locomotive syndrome, trauma, paediatrics, oncology and biomaterials, as well as basic researches.