{"title":"Functionalization of (Z)-N3-(2-Amino-1,2-dicyanovinyl)formamidrazone to Five-Membered N-Heterocycles and Their Antimicrobial Activity","authors":"A. Al-Azmi, E. John","doi":"10.1134/S1070428024090173","DOIUrl":null,"url":null,"abstract":"<p>Various five-membered heterocyclic compounds and highly functionalized open intermediates were simply synthesized by reacting (<i>Z</i>)–<i>N</i><sup>3</sup>-(2-amino-1,2-dicyanovinyl)formamidrazone with selected reagents containing electrophilic carbon. The synthesized compounds were tested for antimicrobial activity and were found to have moderate antimicrobial effects.</p>","PeriodicalId":766,"journal":{"name":"Russian Journal of Organic Chemistry","volume":"60 9","pages":"1744 - 1751"},"PeriodicalIF":0.8000,"publicationDate":"2024-11-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Russian Journal of Organic Chemistry","FirstCategoryId":"92","ListUrlMain":"https://link.springer.com/article/10.1134/S1070428024090173","RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"CHEMISTRY, ORGANIC","Score":null,"Total":0}
引用次数: 0
Abstract
Various five-membered heterocyclic compounds and highly functionalized open intermediates were simply synthesized by reacting (Z)–N3-(2-amino-1,2-dicyanovinyl)formamidrazone with selected reagents containing electrophilic carbon. The synthesized compounds were tested for antimicrobial activity and were found to have moderate antimicrobial effects.
期刊介绍:
Russian Journal of Organic Chemistry is an international peer reviewed journal that covers all aspects of modern organic chemistry including organic synthesis, theoretical organic chemistry, structure and mechanism, and the application of organometallic compounds in organic synthesis.