Comparative effectiveness of multi-sensory interventions for reducing pain among premature infants: A systematic review and network meta-analysis

IF 7.5 1区医学 Q1 NURSING

International Journal of Nursing Studies Pub Date : 2024-10-31 DOI:10.1016/j.ijnurstu.2024.104947

Mei-di Shen , Xiang-dong Ding , Li Fu , Hong-xiao He , Si-bing Chen , Yin-chu Hu , Chong-kun Wang , Li-hua Ren

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引用次数: 0

Abstract

Background

A series of multi-sensory interventions are proved to be effective in reducing pain among premature infants. Nevertheless, there lacks a comparison of these interventions to find the most suitable and optimal one for clinical decision-making.

Objective

This systematic review and network meta-analysis aims to compare the effectiveness of various multi-sensory interventions, and to identify the optimal intervention for alleviating pain in premature infants.

Methods

A comprehensive literature search was performed on August 19, 2024 to identify pertinent clinical trials. The Cochrane Risk of Bias (version 2) was used to assess the quality and potential bias of each included study. Network meta-analysis was used to assess the effectiveness of various interventions and to identify the optimal ones.

Results

A total of 18 clinical trials involving 1408 premature infants were included. Three multi-sensory interventions were shown to be superior to routine practice in reducing pain among premature infants, including tactile-kinesthetic intervention, tactile-auditory intervention and tactile-visual-gustatory-olfactory intervention (all, P < 0.05). Among these interventions, tactile-kinesthetic intervention ranks the best for its effectiveness in alleviating procedural pain among premature infants. Subgroup network meta-analysis demonstrated that the tactile-visual-gustatory-auditory-olfactory intervention ranked the best for its effectiveness in reducing pain from invasive procedures, with the tactile-auditory intervention best for non-invasive procedures.

Conclusions

Our study suggests that cautious assessment and identification should be prioritized to select appropriate multi-sensory interventions based on pain procedures, thus to effectively reduce pain in premature infants. Subsequent studies are needed to refine and optimize these strategies for broader application.

PROSPERO registry

CRD42024510352.

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多感官干预对减轻早产儿疼痛的比较效果：系统综述和网络荟萃分析

背景事实证明，一系列多感官干预措施可有效减轻早产儿的疼痛。本系统综述和网络荟萃分析旨在比较各种多感官干预措施的有效性，并确定减轻早产儿疼痛的最佳干预措施。方法于 2024 年 8 月 19 日进行了全面的文献检索，以确定相关的临床试验。采用 Cochrane 偏倚风险（第 2 版）评估每项纳入研究的质量和潜在偏倚。采用网络荟萃分析法评估各种干预措施的有效性，并确定最佳干预措施。结果表明，三种多感官干预措施在减轻早产儿疼痛方面优于常规做法，包括触觉-动觉干预措施、触觉-听觉干预措施和触觉-视觉-口腔-嗅觉干预措施（所有干预措施的P均为0.05）。在这些干预措施中，触觉-动觉干预对减轻早产儿手术疼痛的效果最好。亚组网络荟萃分析表明，触觉-视觉-口腔-听觉-嗅觉干预在减轻侵入性手术疼痛方面的效果最好，而触觉-听觉干预在减轻非侵入性手术疼痛方面的效果最好。结论我们的研究表明，应优先进行谨慎的评估和识别，根据疼痛程序选择适当的多感官干预措施，从而有效减轻早产儿的疼痛。需要进行后续研究，以完善和优化这些策略，使其得到更广泛的应用。PROSPERO registryCRD42024510352。

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来源期刊

International Journal of Nursing Studies 医学-护理

CiteScore

15.00

自引率

2.50%

发文量

181

审稿时长

21 days

期刊介绍： The International Journal of Nursing Studies (IJNS) is a highly respected journal that has been publishing original peer-reviewed articles since 1963. It provides a forum for original research and scholarship about health care delivery, organisation, management, workforce, policy, and research methods relevant to nursing, midwifery, and other health related professions. The journal aims to support evidence informed policy and practice by publishing research, systematic and other scholarly reviews, critical discussion, and commentary of the highest standard. The IJNS is indexed in major databases including PubMed, Medline, Thomson Reuters - Science Citation Index, Scopus, Thomson Reuters - Social Science Citation Index, CINAHL, and the BNI (British Nursing Index).