Phase spectrogram of EEG from S-transform Enhances epileptic seizure detection

Abstract

Automatic epilepsy seizure detection has high clinical value since it can alleviate the burden of manual monitoring. Nevertheless, it remains a technically challenging task to achieve a reliable system. In this study, we investigated the significance of the phase information in EEG signals in seizure detection using machine learning. We used the Stockwell transform (S-transform) to extract both phase and power spectra of the EEG signal in epilepsy patients. A dual-stream convolution neural network (CNN) model was adopted as the classifier, which takes both spectra as inputs. We demonstrated that the phase input allows the CNN model to capture the heightened phase synchronization among EEG channels in seizure and add network attention to both the low- and high-frequency features of the inputs in the CHB-MIT and Bonn databases. We improved the detection AUC-ROC by 6.68% on the CHB-MIT database when adding phase inputs to the power inputs. By incorporating a channel fusion post-processing to the outputs of this CNN model, it achieves a sensitivity and specificity of 79.59% and 92.23%, respectively, surpassing some of the state-of-the-art methods. Our results show that the phase inputs are useful features in seizure detection. This discovery has significant implications for improving the effectiveness of automatic seizure detection systems.