Heart Rate Variability and Heart Failure with Reduced Ejection Fraction: A Systematic Review of Literature.

IF 2.4 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS

Current Cardiology Reviews Pub Date : 2024-11-01 DOI:10.2174/011573403X327105241021180916

Michiaki Nagai, Hallum Ewbank, Yukiko Nakano, Benjamin J Scherlag, Sunny S Po, Tarun W Dasari

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Abstract

Introduction: Autonomic impairment is a hallmark of heart failure with reduced ejection fraction (HFrEF). While there have been studies on general values for each index of heart rate variability (HRV) analysis in HFrEF, a systematic review comprehensively examining representative values in HFrEF is lacking.

Methods: We searched PubMed, Embase, and Cochrane databases to extract studies reporting representative values of HRV metrics in HFrEF.

Results: A total of 470 HFrEF patients from 6 studies were included in the review. In general, time and frequency domains were abnormally lower in HFrEF, portending a worse prognosis. In HFrEF, the mean or median value of the standard deviation of NN interval, root mean square successive difference, pNN50, and low-frequency power/high-frequency power were 40 to 121 msec, 19 to 62 msec, 1.3 to 14%, and 1.00 to 1.73, respectively.

Conclusion: In this systematic review, most HRV metrics were found to be calculated from 24- hour Holter recordings and were lower in HFrEF patients with poor prognosis.

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心率变异与射血分数减低性心力衰竭：系统性文献综述

简介自主神经功能障碍是射血分数降低型心力衰竭（HFrEF）的特征之一。虽然已有研究对 HFrEF 中心率变异性（HRV）分析的各项指标的一般值进行了研究，但目前还缺乏对 HFrEF 中代表性值进行全面研究的系统性综述：我们检索了 PubMed、Embase 和 Cochrane 数据库，以提取报告 HFrEF 中心率变异指标代表值的研究：结果：共有来自 6 项研究的 470 名 HFrEF 患者被纳入综述。一般来说，HFrEF 的时域和频域异常降低，预示着预后较差。在 HFrEF 中，NN 间期标准差、均方根连续差、pNN50 和低频功率/高频功率的平均值或中值分别为 40 至 121 毫秒、19 至 62 毫秒、1.3 至 14% 和 1.00 至 1.73：在这篇系统性综述中发现，大多数心率变异指标是通过 24 小时 Holter 记录计算得出的，预后不良的 HFrEF 患者的心率变异指标较低。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current Cardiology Reviews CARDIAC & CARDIOVASCULAR SYSTEMS-

CiteScore

3.70

自引率

10.50%

发文量

117

期刊介绍： Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.