Health symptoms and cosmetic silicone breast implants: A retrospective cohort study

IF 2 3区医学 Q2 SURGERY

Journal of Plastic Reconstructive and Aesthetic Surgery Pub Date : 2024-10-18 DOI:10.1016/j.bjps.2024.10.026

A.S. Lieffering , L. Ramerman , J.E. Hommes , H.A. Rakhorst , M.A.M. Mureau , R.R.W.J. van der Hulst , R.A. Verheij

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引用次数: 0

Abstract

Background

There has been a growing concern about a possible causal relationship between silicone breast implants (SBIs) and health symptoms, referred to as breast implant illness. This study assessed the association between SBIs for cosmetic augmentation and health symptoms.

Methods

This retrospective cohort study used the data from the Dutch Breast Implant Registry and Nivel Primary Care Database. A total of 688 women with cosmetic SBIs were age-matched with 1301 women without SBIs. The occurrence of 13 health symptoms presented in general practice was assessed 1 year before implantation until 3 years after implantation. Comparisons were made regarding the number of symptoms and general practice consultations, before and after implantation and between the two groups.

Results

Women with SBIs were more likely to experience three or more distinct health symptoms and a combination of multiple symptoms with multiple consultations during follow-up than women without SBIs (adjusted OR 1.44, 95% CI 1.06 to 1.96; adjusted OR 1.44, 95% CI 1.04 to 2.00, respectively). Women with SBIs also had more than twice the likelihood of manifesting these outcomes in the second year after implantation compared to the first year before implantation (OR 2.13, 95% CI 1.27 to 3.57; OR 2.13, 95% CI 1.22 to 3.72, respectively).

Conclusions

Women with cosmetic SBIs had increased odds of developing health symptoms after implantation compared to those before implantation and to women without SBIs. These results suggest an association between health symptoms and cosmetic SBIs that needs further research to explore whether there is causality or residual confounding.

查看原文本刊更多论文

健康症状与硅胶假体隆胸：一项回顾性队列研究。

背景：硅胶隆胸（SBI）与健康症状（即隆胸疾病）之间可能存在的因果关系日益受到关注。本研究评估了硅胶隆胸与健康症状之间的关系：这项回顾性队列研究使用了荷兰乳房植入物登记处和 Nivel 初级保健数据库的数据。共有 688 名接受过隆胸整形手术的女性与 1301 名未接受过隆胸整形手术的女性进行了年龄匹配。对植入前 1 年至植入后 3 年期间在全科医生处出现的 13 种健康症状进行了评估。对植入前后以及两组妇女的症状数量和全科就诊情况进行了比较：结果表明：与无 SBI 的妇女相比，有 SBI 的妇女在随访期间更有可能出现三种或三种以上不同的健康症状，以及多种症状并发和多次就诊（调整 OR 分别为 1.44，95% CI 为 1.06 至 1.96；调整 OR 分别为 1.44，95% CI 为 1.04 至 2.00）。有SBI的妇女在植入后第二年出现这些结果的可能性也是植入前第一年的两倍多（OR 2.13，95% CI 1.27至3.57；OR 2.13，95% CI 1.22至3.72）：与植入前和没有 SBI 的妇女相比，有 SBI 美容的妇女在植入后出现健康症状的几率更高。这些结果表明，健康症状与美容性 SBIs 之间存在关联，需要进一步研究探讨两者之间是否存在因果关系或残余混杂因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Journal of Plastic Reconstructive and Aesthetic Surgery 医学-外科

CiteScore

3.10

自引率

11.10%

发文量

578

审稿时长

3.5 months

期刊介绍： JPRAS An International Journal of Surgical Reconstruction is one of the world''s leading international journals, covering all the reconstructive and aesthetic aspects of plastic surgery. The journal presents the latest surgical procedures with audit and outcome studies of new and established techniques in plastic surgery including: cleft lip and palate and other heads and neck surgery, hand surgery, lower limb trauma, burns, skin cancer, breast surgery and aesthetic surgery.