Odontoid remodeling with occipital condyle stabilization in patients with metastatic C2 involvement.

IF 1.4 Q2 OTORHINOLARYNGOLOGY
Mehmet Yigit Akgun, Nazenin Durmus, Caner Gunerbuyuk, Sezer Onur Gunara, Tunc Oktenoglu, Mehdi Sasani, Ozkan Ates, Ali Fahir Ozer
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Abstract

The occipitocervical junction (OCJ) is a complex anatomical region crucial for protecting the lower brain stem, upper spinal cord, and lower cranial nerves. Instability in this area can lead to severe outcomes such as chronic pain, neurological deficits, or death. Various surgical techniques have been developed for OCJ stabilization, particularly using occipital condyle screws, which have shown promise in providing stability and preserving neck rotation. This article presents two cases of OCJ instability caused by metastatic involvement of the C2 vertebra, managed successfully with occipital condyle screw fixation. The first case involved a 22-year-old female with Ewing sarcoma metastasis, and the second case involved a 62-year-old male with multiple myeloma. Both patients exhibited significant improvements in neurological function and cervical stability postoperatively, with observable den remodeling. Our findings suggest that occipital condyle screw fixation is not only feasible but also effective in managing OCJ instability due to metastatic disease. Detailed preoperative evaluation and the use of advanced intraoperative imaging technologies, such as the O-arm and neuronavigation, are essential for maximizing safety and ensuring optimal outcomes. This study underscores the potential of occipital condyle screw fixation as a primary surgical method for stabilizing the OCJ in appropriate cases.

对 C2 受累转移患者进行枕骨髁稳定重塑。
枕颈交界处(OCJ)是一个复杂的解剖区域,对保护下脑干、上脊髓和下颅神经至关重要。该区域的不稳定性可导致慢性疼痛、神经功能缺损或死亡等严重后果。目前已开发出多种用于稳定 OCJ 的手术技术,尤其是使用枕骨髁螺钉,这些技术在提供稳定性和保持颈部旋转方面已显示出良好的前景。本文介绍了两例因C2椎体转移性受累而导致的OCJ不稳定病例,这两例病例均采用枕骨髁螺钉固定术成功治愈。第一例患者是一名 22 岁的女性,患有尤文肉瘤转移;第二例患者是一名 62 岁的男性,患有多发性骨髓瘤。两名患者术后的神经功能和颈椎稳定性均有明显改善,并可观察到穴位重塑。我们的研究结果表明,枕骨髁螺钉固定术不仅可行,而且能有效治疗转移性疾病导致的 OCJ 不稳定。详细的术前评估和使用先进的术中成像技术(如 O 型臂和神经导航)对于最大限度地提高安全性和确保最佳治疗效果至关重要。这项研究强调了枕骨髁螺钉固定术作为一种主要手术方法在适当病例中稳定 OCJ 的潜力。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
1.90
自引率
9.10%
发文量
57
审稿时长
12 weeks
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