Decoding Sex Differences: How GABA Shapes Drosophila Behavior.

IF 5.8 1区农林科学 Q1 BIOLOGY

Current opinion in insect science Pub Date : 2024-10-27 DOI:10.1016/j.cois.2024.101293

Saheli Sengupta, Kravitz A Edward

引用次数: 0

Abstract

Sexually dimorphic behaviors are fundamental to the biology of many species, including fruit flies and humans. These behaviors are regulated primarily by sex-specific neural circuits or the sex-specific modulation of shared neuronal substrates. In fruit flies, GABAergic neurotransmission plays a critical role in governing sexually dimorphic behaviors such as courtship, copulation, and aggression. This review explores the intricate roles of GABAergic neurons in these behaviors, and focuses on how sex-specific differences in GABAergic circuits contribute to their modulation and execution. By examining these mechanisms in Drosophila, we reveal broader implications for understanding sexual dimorphism in more complex organisms.

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解码性别差异：GABA 如何塑造果蝇的行为

性别二态行为是包括果蝇和人类在内的许多物种的基本生物学行为。这些行为主要由性别特异性神经回路或性别特异性调节共享神经元底物来调控。在果蝇中，GABA 能神经递质在求偶、交配和攻击等性别二态行为中起着关键作用。这篇综述探讨了 GABA 能神经元在这些行为中的复杂作用，并重点研究了 GABA 能回路中的性别特异性差异如何对这些行为的调节和执行起作用。通过研究果蝇的这些机制，我们揭示了了解更复杂生物的性二态性的更广泛意义。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current opinion in insect science BIOLOGYECOLOGYENTOMOLOGY-ECOLOGY

CiteScore

10.40

自引率

1.90%

发文量

113

期刊介绍： Current Opinion in Insect Science is a new systematic review journal that aims to provide specialists with a unique and educational platform to keep up–to–date with the expanding volume of information published in the field of Insect Science. As this is such a broad discipline, we have determined themed sections each of which is reviewed once a year. The following 11 areas are covered by Current Opinion in Insect Science. -Ecology -Insect genomics -Global Change Biology -Molecular Physiology (Including Immunity) -Pests and Resistance -Parasites, Parasitoids and Biological Control -Behavioural Ecology -Development and Regulation -Social Insects -Neuroscience -Vectors and Medical and Veterinary Entomology There is also a section that changes every year to reflect hot topics in the field. Section Editors, who are major authorities in their area, are appointed by the Editors of the journal. They divide their section into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasized. Section Editors commission articles from leading scientists on each topic that they have selected and the commissioned authors write short review articles in which they present recent developments in their subject, emphasizing the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the previous year.