Trends of Artificial Intelligence (AI) Use in Drug Targets, Discovery and Development: Current Status and Future Perspectives.

IF 3 4区医学 Q2 PHARMACOLOGY & PHARMACY

Current drug targets Pub Date : 2024-10-29 DOI:10.2174/0113894501322734241008163304

Manmayee Mohapatra, Chittaranjan Sahu, Snehamayee Mohapatra

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引用次数: 0

Abstract

The applications of artificial intelligence (AI) in pharmaceutical sectors have advanced drug discovery and development methods. AI has been applied in virtual drug design, molecule synthesis, advanced research, various screening methods, and decision-making processes. In the fourth industrial revolution, when medical discoveries are happening swiftly, AI technology is essential to reduce the costs, effort, and time in the pharmaceutical industry. Further, it will aid "genome-based medicine" and "drug discovery." AI may prepare proactive databases according to diseases, disorders, and appropriate usage of drugs which will facilitate the required data for the process of drug development. The application of AI has improved clinical trials on patient selection in a population, stratification, and sample assessment such as biomarkers, effectiveness measures, dosage selection, and trial length. Various studies suggest AI could be perform better compared to conventional techniques in drug discovery. The present review focused on the positive impact of AI in drug discovery and development processes in the pharmaceutical industry and beneficial usage in health sectors as well.

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人工智能（AI）在药物靶点、发现和开发中的应用趋势：现状与未来展望》。

人工智能（AI）在制药领域的应用推动了药物发现和开发方法的发展。人工智能已被应用于虚拟药物设计、分子合成、高级研究、各种筛选方法和决策过程。在第四次工业革命中，医学发现日新月异，人工智能技术对于降低制药行业的成本、减少工作量和缩短时间至关重要。此外，它还将有助于 "基于基因组的医学 "和 "药物发现"。人工智能可以根据疾病、失调和药物的适当用法准备主动数据库，这将有助于药物开发过程中所需的数据。人工智能的应用改善了临床试验中对人群中患者的选择、分层和样本评估，如生物标志物、有效性测量、剂量选择和试验长度。多项研究表明，与传统技术相比，人工智能在药物发现方面可以发挥更好的作用。本综述侧重于人工智能在制药业药物发现和开发过程中的积极影响，以及在卫生部门的有益应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Current drug targets 医学-药学

CiteScore

6.20

自引率

0.00%

发文量

127

审稿时长

3-8 weeks

期刊介绍： Current Drug Targets aims to cover the latest and most outstanding developments on the medicinal chemistry and pharmacology of molecular drug targets e.g. disease specific proteins, receptors, enzymes, genes. Current Drug Targets publishes guest edited thematic issues written by leaders in the field covering a range of current topics of drug targets. The journal also accepts for publication mini- & full-length review articles and drug clinical trial studies. As the discovery, identification, characterization and validation of novel human drug targets for drug discovery continues to grow; this journal is essential reading for all pharmaceutical scientists involved in drug discovery and development.