Improvement in Health-Related Quality of Life and Symptoms Following Lipedema Liposuction: A Longitudinal Study.

IF 1.4 4区 医学 Q3 SURGERY
Vasu Karri
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引用次数: 0

Abstract

Background: Lipedema is a chronic fat disorder characterized by disproportionate fat deposition in the lower limbs, leading to pain, mobility issues and reduced health related quality of life (HRQoL).There is growing evidence that liposuction of the excess fat not only reduces soft tissue pain but also improves HRQoL. The published data, however, remain limited, and there are no studies of liposuction in the UK lipedema population. This study aimed to evaluate the effectiveness of liposuction on HRQoL and symptoms in UK lipedema patients using 2 HRQoL instruments and a Lipedema Symptom Scale.

Patient and methods: Lipedema patients undergoing liposuction between January 2016 and December 2021 completed Short-Form Health Survey (SF-36), World Health Organization Quality-of-Life Assessment (WHOQOL-BREF), and 17-question Lipedema Symptom Scale preoperatively and postoperatively. Paired t test was used to compare the preoperative and postoperative mean scores of the different domains of the SF-36 and WHOQOL-BREF and preoperative and postoperative mean scores for the lipedema symptom scale. Paired t test was also used to compare preoperative and postoperative SF-36 scores to age-matched normative data for the English population to assess the extent of HRQoL improvement relative to the general population.

Results: Seventy-six women were included in the study with a mean age of 46.4 ± 12 years. Mean follow-up (interval between first liposuction surgery and postoperative completion of the instruments) was 25.3 ± 23.2 months. There was significant improvement in all SF-36 and WHOQOL-BREF domains postoperatively (P < 0.001). Compared with age-matched normative data, postoperative SF-36 scores remained lower in physical functioning, social functioning, and general health. Postoperative results also showed a highly significant improvement (P < 0.001) across all 17 items of the Lipedema Symptom Scale.

Conclusion: This longitudinal study indicates liposuction is an effective treatment for improving HRQoL and symptoms in lipedema patients, although it may not completely restore HRQoL to normative levels. Limitations include potential selection bias, sampling bias, and the need for longer follow-up. The findings support liposuction as a first-line treatment for lipedema and could inform decision-making for both patients and policymakers.

脂肪水肿吸脂术后与健康相关的生活质量和症状的改善:一项纵向研究
背景:脂肪性水肿是一种慢性脂肪疾病,其特点是脂肪不成比例地沉积在下肢,导致疼痛、行动不便和与健康相关的生活质量(HRQoL)下降。然而,已发表的数据仍然有限,也没有针对英国脂肪性水肿人群的吸脂研究。本研究旨在使用两种 HRQoL 工具和脂肪性水肿症状量表,评估脂肪抽吸术对英国脂肪性水肿患者的 HRQoL 和症状的影响:2016年1月至2021年12月期间接受吸脂术的脂肪性水肿患者在术前和术后完成了短表健康调查(SF-36)、世界卫生组织生活质量评估(WHOQOL-BREF)和17个问题的脂肪性水肿症状量表。采用配对 t 检验比较 SF-36 和 WHOQOL-BREF 不同领域的术前和术后平均得分,以及脂肪性水肿症状量表的术前和术后平均得分。此外,还使用配对t检验将术前和术后的SF-36评分与英国人口的年龄匹配常模数据进行比较,以评估相对于普通人口的HRQoL改善程度:研究共纳入 76 名女性,平均年龄为 46.4 ± 12 岁。平均随访时间(从首次吸脂手术到术后完成仪器操作的时间间隔)为 25.3 ± 23.2 个月。术后,SF-36 和 WHOQOL-BREF 各项指标均有明显改善(P < 0.001)。与年龄匹配的常模数据相比,术后 SF-36 在身体功能、社会功能和一般健康方面的得分仍然较低。术后结果还显示,脂肪性水肿症状量表的所有 17 个项目都有非常显著的改善(P < 0.001):这项纵向研究表明,吸脂术是改善脂肪性水肿患者 HRQoL 和症状的有效治疗方法,尽管它可能无法将 HRQoL 完全恢复到正常水平。不足之处包括潜在的选择偏差、抽样偏差以及需要更长时间的随访。研究结果支持将吸脂术作为脂肪性水肿的一线治疗方法,并可为患者和决策者的决策提供参考。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
2.70
自引率
13.30%
发文量
584
审稿时长
6 months
期刊介绍: The only independent journal devoted to general plastic and reconstructive surgery, Annals of Plastic Surgery serves as a forum for current scientific and clinical advances in the field and a sounding board for ideas and perspectives on its future. The journal publishes peer-reviewed original articles, brief communications, case reports, and notes in all areas of interest to the practicing plastic surgeon. There are also historical and current reviews, descriptions of surgical technique, and lively editorials and letters to the editor.
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