Interleukin-2 receptor levels are increased in blood of heart transplant patients during infections.

Diagnostic and clinical immunology Pub Date : 1987-01-01
V Stolc, J R Krause
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Abstract

Increased levels of soluble interleukin-2 (IL-2) receptor were found in plasma of six patients after the heart transplantation. The levels peaked the first week after transplantation and then gradually decreased to normal levels. The moderate episodes of heart transplant rejection did not affect the IL-2 receptor levels in comparison to transplant recipients without the rejection episodes. However, the transplant patients with pneumonia had the IL-2 receptor levels ten times higher than healthy controls. Hence, the IL-2 receptor levels in plasma might be a valuable indicator of the dynamics of the acute infection in heart transplant recipients.

心脏移植患者感染期间血液中白细胞介素-2受体水平升高。
6例心脏移植术后患者血浆中可溶性白细胞介素-2 (IL-2)受体升高。移植后第一周达到高峰,随后逐渐降至正常水平。与未发生排斥反应的移植受者相比,中度心脏移植排斥反应不影响IL-2受体水平。然而,肺炎移植患者的IL-2受体水平比健康对照组高10倍。因此,血浆IL-2受体水平可能是心脏移植受者急性感染动态的一个有价值的指标。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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