Anouk Corbeau , Pien van Gastel , Piotr A. Wielopolski , Nick de Jong , Carien L. Creutzberg , Uulke A. van der Heide , Stephanie M. de Boer , Eleftheria Astreinidou
{"title":"Accuracy, repeatability, and reproducibility of water-fat magnetic resonance imaging in a phantom and healthy volunteer","authors":"Anouk Corbeau , Pien van Gastel , Piotr A. Wielopolski , Nick de Jong , Carien L. Creutzberg , Uulke A. van der Heide , Stephanie M. de Boer , Eleftheria Astreinidou","doi":"10.1016/j.phro.2024.100651","DOIUrl":null,"url":null,"abstract":"<div><div>Bone marrow (BM) damage due to chemoradiotherapy can increase BM fat in cervical cancer patients. Water-fat magnetic resonance (MR) scans were performed on a phantom and a healthy female volunteer to validate proton density fat fraction accuracy, reproducibility, and repeatability across different vendors, field strengths, and protocols. Phantom measurements showed a high accuracy, high repeatability, and excellent reproducibility. Volunteer measurements had an excellent intra- and interreader reliability, good repeatability, and moderate to good reproducibility. Water-fat MRI show potential for quantification of longitudinal vertebral BM fat changes. Further studies are needed to validate and extend these findings for broader clinical applicability.</div></div>","PeriodicalId":36850,"journal":{"name":"Physics and Imaging in Radiation Oncology","volume":"32 ","pages":"Article 100651"},"PeriodicalIF":3.4000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Physics and Imaging in Radiation Oncology","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2405631624001210","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ONCOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Bone marrow (BM) damage due to chemoradiotherapy can increase BM fat in cervical cancer patients. Water-fat magnetic resonance (MR) scans were performed on a phantom and a healthy female volunteer to validate proton density fat fraction accuracy, reproducibility, and repeatability across different vendors, field strengths, and protocols. Phantom measurements showed a high accuracy, high repeatability, and excellent reproducibility. Volunteer measurements had an excellent intra- and interreader reliability, good repeatability, and moderate to good reproducibility. Water-fat MRI show potential for quantification of longitudinal vertebral BM fat changes. Further studies are needed to validate and extend these findings for broader clinical applicability.