PHSOR06 Presentation Time: 9:25 AM

IF 1.7 4区 医学 Q4 ONCOLOGY
Sharbacha Edward PhD in Medical Physics, Justin Mikell PhD, Jose Garcia-Ramirez MS, Michael B. Altman PhD, Phillip D. Wall PhD, Anamaria Guta MS, Jason LaBrash BS, Jessika A. Contreras MD, Jacqueline E. Zoberi PhD
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引用次数: 0

Abstract

Purpose

Two high dose rate (HDR) remote afterloaders (RALs) were recently accepted and commissioned for use in our clinic. These RALs are unique in that prior to treatment, they measure each connected applicator + transfer guide tube (TGT) channel length with the dummy wire. If this measurement deviation is within some user-specified tolerance, the RAL automatically adjusts the planned channel length (and subsequent dwell positions) used for treatment by the active wire. This work evaluates the positional accuracy of these units and reports their performance over the first few months of gynecologic patient treatments.

Materials and Methods

Acceptance testing and commissioning were performed for both units: RAL1 in August 2023, and RAL2 in November 2023. Applicator + TGT channel length verification tests were performed as part of this process. Channel lengths were measured with two independent ruler systems provided by the manufacturer. Manually measured channel lengths were within 0.5 mm of the baseline nominal values provided by the manufacturer. In order to quantify RAL positional accuracy, rigid fixed length applicators - including tandems, ovoids, cylinders, and Simon-Heyman capsules - were affixed to radiochromic film, and double exposure irradiations were performed. First, they were irradiated using a mobile C-Arm fluoroscopy unit. An autoradiograph was then acquired using mock treatment plans designed using nominal channel lengths as the planned lengths, and delivered by the RALs using an ideal applicator setup, i.e. minimizing curvature of TGTs. We configured the RAL to automatically adjust dwell positions when the difference between the RAL-measured and planned channel lengths were within 2 mm. Dwell position deviations measured on film were compared with differences between planned and RAL-measured channel lengths. The record and verify system's treatment summary was queried to extract the RALs’ measured channel lengths. The performance of each RAL was assessed over time by comparing the treatment summary channel lengths for patient treatments with the planned values.

Results

Double exposure films indicated that, on average, dwell positions deviated towards the applicator tip by 0.8mm (max=1.5mm). Mean difference between planned and RAL-measured channel lengths was 0.5 mm (max=0.9mm). On both RALs, more curved applicators had larger length deviations during commissioning and patient treatments. This increased curvature resulted in larger overestimates of channel length, up to 1.7mm for ovoids. Ovoid channel length deviations were similar for left and right ovoids on RAL1 at just over 1mm initially, and decreased over a 23 week period to be <1mm. The deviations however remained steady for RAL2 over 10 weeks of treatment, with 90% of all values being >1mm(Fig.1). Left ovoids showed larger deviation than right (1.45 vs 1.18mm respectively) (p<0.01).

Conclusions

Two HDR RALs were commissioned, and the inherent channel length verification measurement and adjustment feature was tested and validated as part of physics commissioning tests of the units. Channel length deviations were as high as 1.7mm for some applicators but gradually decreased overtime. The most curved applicator, ovoids, had the highest deviation.
PHSOR06 演讲时间:上午 9:25
目的最近,两台高剂量率(HDR)远程后装载器(RAL)被接受并委托在本诊所使用。这些 RAL 的独特之处在于,在治疗前,它们会用假线测量每个连接的涂抹器+传输导管(TGT)通道的长度。如果测量偏差在用户指定的公差范围内,RAL 就会自动调整有源导线用于治疗的计划通道长度(以及随后的停留位置)。这项工作评估了这些设备的定位精度,并报告了它们在妇科病人治疗的最初几个月中的表现:RAL1 于 2023 年 8 月完成,RAL2 于 2023 年 11 月完成。在此过程中进行了涂抹器 + TGT 通道长度验证测试。通道长度由制造商提供的两个独立尺子系统进行测量。手动测量的通道长度与制造商提供的基准标称值相差 0.5 毫米以内。为了量化 RAL 的定位精度,将固定长度的硬质涂抹器(包括串珠、卵圆形、圆柱形和西蒙-海曼胶囊)贴在放射性变色胶片上,并进行双重曝光辐照。首先,使用移动式 C-Arm 透视装置对它们进行辐照。然后使用模拟治疗方案获取自动放射照片,模拟治疗方案的设计以标称通道长度作为计划长度,并由 RAL 使用理想的涂抹器设置进行涂抹,即最大限度地减少 TGT 的曲率。我们对 RAL 进行了配置,当 RAL 测量的通道长度与计划的通道长度之差在 2 毫米以内时,RAL 会自动调整停留位置。将胶片上测量到的停留位置偏差与计划通道长度和 RAL 测量通道长度之间的差异进行比较。通过查询记录和验证系统的治疗摘要,提取 RAL 的测量通道长度。通过比较患者治疗的治疗摘要通道长度与计划值,评估每个 RAL 的性能。结果双曝光胶片显示,停留位置平均偏离涂抹器尖端 0.8 毫米(最大=1.5 毫米)。计划的通道长度与 RAL 测量的通道长度平均相差 0.5 毫米(最大值=0.9 毫米)。在两种 RAL 上,弧度较大的涂抹器在调试和患者治疗期间的长度偏差较大。弧度增大导致通道长度的高估值增大,椭圆形通道的高估值高达 1.7 毫米。RAL1 的左侧和右侧椭圆形通道长度偏差相似,最初略高于 1 毫米,在 23 周内下降到 1 毫米。然而,RAL2 的偏差在 10 周的治疗中保持稳定,90% 的偏差值为 1 毫米(图 1)。结论两台 HDR RAL 已投入使用,作为设备物理调试测试的一部分,对固有的通道长度验证测量和调整功能进行了测试和验证。一些涂抹器的通道长度偏差高达 1.7 毫米,但随着时间的推移逐渐减小。最弯曲的涂抹器(椭圆形)偏差最大。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Brachytherapy
Brachytherapy 医学-核医学
CiteScore
3.40
自引率
21.10%
发文量
119
审稿时长
9.1 weeks
期刊介绍: Brachytherapy is an international and multidisciplinary journal that publishes original peer-reviewed articles and selected reviews on the techniques and clinical applications of interstitial and intracavitary radiation in the management of cancers. Laboratory and experimental research relevant to clinical practice is also included. Related disciplines include medical physics, medical oncology, and radiation oncology and radiology. Brachytherapy publishes technical advances, original articles, reviews, and point/counterpoint on controversial issues. Original articles that address any aspect of brachytherapy are invited. Letters to the Editor-in-Chief are encouraged.
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