Structural design and biomechanical analysis of a combined titanium and polyetheretherketone cage based on PE-PLIF fusion.

IF 2.6 4区 医学 Q2 COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
Lei Ma, Yutang Xie, Kai Zhang, Jing Chen, Yanqin Wang, Liming He, Haoyu Feng, Weiyi Chen, Meng Zhang, Yanru Xue, Xiaogang Wu, Qiang Li
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引用次数: 0

Abstract

In lumbar spinal fusion, the titanium cage tends to cause stress shielding due to their high elastic modulus, which can lead to degenerative lesions in adjacent spinal segments. Furthermore, polyetheretherketone (PEEK) cages have certain material characteristics that do not promote bone ingrowth and fusion stability. In this study, a new cage was designed, and its biomechanical performance in percutaneous endoscopic posterior lumbar interbody fusion (PE-PLIF) was analyzed using the finite element (FE) method. A complete model of the L4-L5 lumbar spine was established, and static and harmonic vibration FE analysis models were developed based on it. The biomechanical properties of titanium, PEEK, and combined cage in PE-PLIF fusion were compared. The strain capacity of the combined fusion increased by 9.5% when compared to the titanium fusion. The surgical model under the combined fusion reduces the L5 endplate stress by 12% in the forward flexion condition and the fusion stress by 17% in the vibration condition compared to the model supported by the titanium fusion, and the differences in screw stress and mobility among the three models are not significant in multiple conditions. Consequently, the combined cage demonstrates a certain reduction in the stress-shielding effect when compared to the titanium cage; it has better fusion effect and provides theoretical support and guidance for the design of the clinical fusion cage.

基于 PE-PLIF 融合技术的钛和聚醚醚酮组合笼的结构设计和生物力学分析。
在腰椎融合术中,钛笼由于弹性模量高,容易造成应力屏蔽,从而导致邻近脊柱节段发生退行性病变。此外,聚醚醚酮(PEEK)保持架的某些材料特性不利于骨的生长和融合的稳定性。本研究设计了一种新型椎体笼,并使用有限元(FE)方法分析了其在经皮内窥镜后路腰椎椎间融合术(PE-PLIF)中的生物力学性能。建立了完整的 L4-L5 腰椎模型,并在此基础上开发了静态和谐波振动有限元分析模型。比较了 PE-PLIF 融合术中钛、PEEK 和组合笼的生物力学特性。与钛融合器相比,组合融合器的应变能力提高了 9.5%。与钛融合器支撑的模型相比,组合融合器支撑的手术模型在前屈状态下 L5 终板应力降低了 12%,在振动状态下融合应力降低了 17%,三种模型的螺钉应力和活动度在多种条件下差异不显著。因此,与钛合金保持架相比,组合保持架的应力屏蔽效果有一定程度的降低,具有更好的融合效果,为临床融合保持架的设计提供了理论支持和指导。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
Medical & Biological Engineering & Computing
Medical & Biological Engineering & Computing 医学-工程:生物医学
CiteScore
6.00
自引率
3.10%
发文量
249
审稿时长
3.5 months
期刊介绍: Founded in 1963, Medical & Biological Engineering & Computing (MBEC) continues to serve the biomedical engineering community, covering the entire spectrum of biomedical and clinical engineering. The journal presents exciting and vital experimental and theoretical developments in biomedical science and technology, and reports on advances in computer-based methodologies in these multidisciplinary subjects. The journal also incorporates new and evolving technologies including cellular engineering and molecular imaging. MBEC publishes original research articles as well as reviews and technical notes. Its Rapid Communications category focuses on material of immediate value to the readership, while the Controversies section provides a forum to exchange views on selected issues, stimulating a vigorous and informed debate in this exciting and high profile field. MBEC is an official journal of the International Federation of Medical and Biological Engineering (IFMBE).
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