{"title":"Clinical care guidance in patients with diabetes and metabolic dysfunction-associated steatotic liver disease: A joint consensus.","authors":"Jee-Fu Huang, Tien-Jyun Chang, Ming-Lun Yeh, Feng-Chih Shen, Chi-Ming Tai, Jung-Fu Chen, Yi-Hsiang Huang, Chih-Yao Hsu, Pin-Nan Cheng, Ching-Ling Lin, Chao-Hung Hung, Ching-Chu Chen, Mei-Hsuan Lee, Chun-Chuan Lee, Chih-Wen Lin, Sung-Chen Liu, Hwai-I Yang, Rong-Nan Chien, Chin-Sung Kuo, Cheng-Yuan Peng, Ming-Ling Chang, Chung-Feng Huang, Yi-Sun Yang, Hung-Chih Yang, Han-Chieh Lin, Horng-Yih Ou, Chun-Jen Liu, Chin-Hsiao Tseng, Jia-Horng Kao, Wan-Long Chuang, Chien-Ning Huang, Pei-Jer Chen, Chih-Yuan Wang, Ming-Lung Yu","doi":"10.1097/HC9.0000000000000571","DOIUrl":null,"url":null,"abstract":"<p><p>Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease worldwide, affecting >30% of the global population. Metabolic dysregulation, particularly insulin resistance and its subsequent manifestation as type 2 diabetes mellitus, serves as the fundamental pathogenesis of metabolic liver disease. Clinical evidence of the recent nomenclature evolution is accumulating. The interaction and impacts are bidirectional between MASLD and diabetes in terms of disease course, risk, and prognosis. Therefore, there is an urgent need to highlight the multifaceted links between MASLD and diabetes for both hepatologists and diabetologists. The surveillance strategy, risk stratification of management, and current therapeutic achievements of metabolic liver disease remain the major pillars in a clinical care setting. Therefore, the Taiwan Association for the Study of the Liver (TASL), Taiwanese Association of Diabetes Educators, and Diabetes Association of the Republic of China (Taiwan) collaboratively completed the first guidance in patients with diabetes and MASLD, which provides practical recommendations for patient care.</p>","PeriodicalId":12978,"journal":{"name":"Hepatology Communications","volume":"8 11","pages":""},"PeriodicalIF":5.6000,"publicationDate":"2024-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11524742/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hepatology Communications","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1097/HC9.0000000000000571","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/11/1 0:00:00","PubModel":"eCollection","JCR":"Q1","JCRName":"GASTROENTEROLOGY & HEPATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease worldwide, affecting >30% of the global population. Metabolic dysregulation, particularly insulin resistance and its subsequent manifestation as type 2 diabetes mellitus, serves as the fundamental pathogenesis of metabolic liver disease. Clinical evidence of the recent nomenclature evolution is accumulating. The interaction and impacts are bidirectional between MASLD and diabetes in terms of disease course, risk, and prognosis. Therefore, there is an urgent need to highlight the multifaceted links between MASLD and diabetes for both hepatologists and diabetologists. The surveillance strategy, risk stratification of management, and current therapeutic achievements of metabolic liver disease remain the major pillars in a clinical care setting. Therefore, the Taiwan Association for the Study of the Liver (TASL), Taiwanese Association of Diabetes Educators, and Diabetes Association of the Republic of China (Taiwan) collaboratively completed the first guidance in patients with diabetes and MASLD, which provides practical recommendations for patient care.
代谢功能障碍相关性脂肪性肝病(MASLD)是全球最常见的慢性肝病,影响着全球 30% 以上的人口。代谢失调,尤其是胰岛素抵抗及其随后表现为 2 型糖尿病,是代谢性肝病的基本发病机制。近期命名演变的临床证据正在不断积累。在病程、风险和预后方面,MASLD 和糖尿病之间的相互作用和影响是双向的。因此,肝病学家和糖尿病学家都迫切需要强调 MASLD 与糖尿病之间的多方面联系。新陳代謝肝病的監測策略、風險分層管理及目前的治療成果,仍是臨床照護的主要支柱。因此,台湾肝脏研究学会(TASL)、台湾糖尿病教育工作者协会(Taiwan Association of Diabetes Educators)和中华民国(台湾)糖尿病协会(Diabetes Association of the Republic of China)合作完成了第一份糖尿病合并代谢性肝病患者指南,为患者护理提供了实用建议。
期刊介绍:
Hepatology Communications is a peer-reviewed, online-only, open access journal for fast dissemination of high quality basic, translational, and clinical research in hepatology. Hepatology Communications maintains high standard and rigorous peer review. Because of its open access nature, authors retain the copyright to their works, all articles are immediately available and free to read and share, and it is fully compliant with funder and institutional mandates. The journal is committed to fast publication and author satisfaction.