Diurnal variation in the association between the scan frequency of isCGM and CGM metrics: post hoc analysis of the ISCHIA study.

IF 1.3 Q4 ENDOCRINOLOGY & METABOLISM

Diabetology International Pub Date : 2024-08-19 eCollection Date: 2024-10-01 DOI:10.1007/s13340-024-00749-y

Shu Meguro, Naoki Sakane, Kiminori Hosoda, Yushi Hirota, Arata Itoh, Ken Kato, Noriko Kodani, Akio Kuroda, Munehide Matsuhisa, Junnosuke Miura, Akira Shimada, Atsuhito Tone, Masao Toyoda, Takashi Murata

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引用次数: 0

Abstract

Background and aims: To investigate the association between the frequency of intermittent-scanning continuous glucose monitoring (isCGM) and diurnal variation of time in range (TIR), time above range (TAR), and time below range (TBR), we performed a post hoc analysis of the ISCHIA study, a multicenter, prospective, open-label, randomized crossover study of patients with type 1 diabetes mellitus.

Method: Data of 93 people who completed the ISCHIA study were used. We calculated scan frequency, TAR, TIR, and TBR of four approximately 6-h intervals: 6:00-11:59 (morning), 12:00-17:59 (afternoon), 18:00-23:59 (evening), and 0:00-5:59 (night). The correlation between scan frequency and diurnal variation of CGM metrics was analyzed using nonparametric Spearman correlation analysis.

Results: More frequent scanning was associated with higher TIR in the afternoon (rho = 0.343, P < 0.001), evening (rho = 0.243, P = 0.019), and night (rho = 0.218, P = 0.036); furthermore, it was associated with lower TAR in the afternoon (rho = -0.275, P = 0.008) and TBR in the evening (rho = -0.235, P = 0.024). Concern about the effect of blood glucose fluctuation on social communication affected the number of scans during the day. Concerns about loneliness and hypoglycemia when alone also influenced the number of nighttime scans.

Conclusion: Scan frequency is influenced by psychological factors. Afternoon scans were associated with the highest increase in TIR and decrease in TAR. Evening scans were linked to a reduction in TBR.

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isCGM 扫描频率与 CGM 指标之间的昼夜变化：ISCHIA 研究的事后分析。

背景和目的为了研究间歇扫描连续血糖监测（isCGM）的频率与在量程内时间（TIR）、在量程以上时间（TAR）和在量程以下时间（TBR）的昼夜变化之间的关系，我们对ISCHIA研究进行了事后分析：方法：使用完成 ISCHIA 研究的 93 人的数据。我们计算了四个约 6 小时间隔的扫描频率、TAR、TIR 和 TBR：6:00-11:59（上午）、12:00-17:59（下午）、18:00-23:59（傍晚）和 0:00-5:59（夜间）。使用非参数斯皮尔曼相关分析法分析了扫描频率与 CGM 指标昼夜变化之间的相关性：结果：扫描频率越高，下午的 TIR 越高（rho = 0.343，P 结论：扫描频率受心理因素影响：扫描频率受心理因素影响。下午扫描与 TIR 升高和 TAR 降低的关系最大。晚间扫描与 TBR 的降低有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Diabetology International ENDOCRINOLOGY & METABOLISM-

CiteScore

3.90

自引率

4.50%

发文量

期刊介绍： Diabetology International, the official journal of the Japan Diabetes Society, publishes original research articles about experimental research and clinical studies in diabetes and related areas. The journal also presents editorials, reviews, commentaries, reports of expert committees, and case reports on any aspect of diabetes. Diabetology International welcomes submissions from researchers, clinicians, and health professionals throughout the world who are interested in research, treatment, and care of patients with diabetes. All manuscripts are peer-reviewed to assure that high-quality information in the field of diabetes is made available to readers. Manuscripts are reviewed with due respect for the author''s confidentiality. At the same time, reviewers also have rights to confidentiality, which are respected by the editors. The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.