[Recent evolution of the epidemiology and burden of invasive meningococal disease].

Abstract

RECENT EVOLUTION OF THE EPIDEMIOLOGY AND BURDEN OF INVASIVE MENINGOCOCAL DISEASE. The landscape of invasive meningococcal disease (IMD) has changed considerably since the COVID-19 pandemic. The number of cases has decreased significantly following the non-pharmaceutical interventions employed to counter the pandemic, but vaccination rates were also lower during the pandemic than pre-pandemic levels. Once the health restrictions were lifted, IMD rapidly rebounded, initially with a resurgence in adolescents/young adults, then in other age groups, reaching a higher number of cases in 2023 than in the pre-pandemic period, with profound epidemiological and genotypic changes, particularly for serogroups W and Y. The number of serogroup C cases remains very low, thanks to the protection offered by the serogroup C conjugate vaccination program for children.