Thyroid dysfunction in women with a menopausal syndrome.

IF 2.5 Q2 OBSTETRICS & GYNECOLOGY
Przeglad Menopauzalny Pub Date : 2024-09-01 Epub Date: 2024-10-14 DOI:10.5114/pm.2024.143481
Oksana Pavlovska, Olga Savelyeva, Kateryna Pavlovska
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引用次数: 0

Abstract

Introduction: The thyroid gland has a significant impact on the morphofunctional state of the organs of the female reproductive system, the regulation of the ovarian-menstrual cycle, as well as the age-related decline of the generative and endocrine function of the ovaries.

Material and methods: The study involved 102 women aged 49-62 years, who were divided into 2 groups. Group I included 54 patients who suffered from manifestations of the menopausal syndrome, and the control group comprised 48 patients whose menopausal period proceeded physiologically. All patients underwent clinical, laboratory, and instrumental examinations in accordance with the requirements of modern protocols.

Results: A thyroid dysfunction has a significant impact on the course of menopause. In women who suffered from manifestations of pathological menopause, the thyroid dysfunction was detected in 64.81% of patients, with the most frequently diagnosed being hypothyroid state (61.11%). Among thyroid diseases, chronic autoimmune thyroiditis prevailed (37.04%), and diffuse focal and focal changes were observed in 24.07% of cases. In patients with uncomplicated menopause, thyroid pathology was diagnosed 3.9 times less frequently. No autoimmune thyropathies were identified among the patients in the control group; focal pathology (category TI-RADS1 and TI-RADS2) was detected in 14.58% of cases.

Conclusions: Thyroid dysfunction accompanied by hypothyroidism can be considered as a risk-stratification factor for the development of pathological menopause.

更年期综合征妇女的甲状腺功能障碍。
导言甲状腺对女性生殖系统器官的形态功能状态、卵巢-月经周期的调节以及与年龄相关的卵巢生成和内分泌功能衰退有重要影响:研究涉及 102 名年龄在 49-62 岁之间的妇女,她们被分为两组。第一组包括 54 名患有更年期综合征的患者,对照组包括 48 名更年期顺其自然的患者。所有患者都按照现代方案的要求接受了临床、实验室和仪器检查:结果:甲状腺功能障碍对更年期的进程有重大影响。在出现病理性更年期表现的女性中,64.81%的患者被检测出甲状腺功能障碍,其中最常被诊断出的是甲状腺功能减退症(61.11%)。在甲状腺疾病中,以慢性自身免疫性甲状腺炎为主(37.04%),24.07%的病例出现弥漫性病灶和局灶性病变。在无并发症的更年期患者中,甲状腺病变的诊断率要低3.9倍。对照组患者中未发现自身免疫性甲状腺病;14.58%的病例发现局灶性病变(TI-RADS1和TI-RADS2类别):结论:伴有甲状腺功能减退的甲状腺功能障碍可被视为病理性绝经的风险分级因素。
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来源期刊
Przeglad Menopauzalny
Przeglad Menopauzalny OBSTETRICS & GYNECOLOGY-
CiteScore
3.40
自引率
11.10%
发文量
32
审稿时长
6-12 weeks
期刊介绍: Menopausal Review is a scientific bimonthly aimed at gynecologists and endocrinologists.
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