Autocorrelation of daily resting heart rate: A novel metric of postoperative recovery

IF 3.7 2区医学 Q2 COMPUTER SCIENCE, INFORMATION SYSTEMS

International Journal of Medical Informatics Pub Date : 2024-10-16 DOI:10.1016/j.ijmedinf.2024.105655

Michela Carter , Rui Hua , Megan K. O’Brien , J. Benjamin Pitt , Soyang Kwon , Arun Jayaraman , Hassan MK Ghomrawi , Fizan Abdullah

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引用次数: 0

Abstract

Purpose

Resting heart rate (RHR) is a sensitive indicator of an individual’s physiologic condition. However, its use in clinical practice has been limited due to the wide variation in baseline RHR based on multiple factors, including age, sex, cardiovascular fitness, and comorbidities. The study aims to develop a novel, clinically meaningful metric that is applicable across these conditions, based on day-by-day changes in RHR—the difference in autocorrelation of daily RHR (ACΔ-RHR). We present ACΔ-RHR in the context of monitoring post-discharge recovery for pediatric appendectomy patients.

Methods

Children 3–17 years old who underwent laparoscopic appendectomy for complicated appendicitis from 2019 to 2022 at a tertiary children’s hospital wore a Fitbit for twenty-one postoperative days (POD). Patients without complications were included to describe normative recovery. Using RHR on POD 1–3 as the baseline, autocorrelation of daily RHR was calculated (fixed lag = 1) for POD 3–21. Then, daily ACΔ-RHR was determined by subtracting autocorrelation values between the current and previous day. Means and standard deviations were calculated for daily RHR to estimate on which POD ACΔ-RHR stabilized at 0, representing general RHR stability and recovery from surgery for all patients. Subgroup analyses were performed by age (3–10 years old vs 11–17 years old) and sex.

Results

Thirty-one patients were included (58.1 % 3–10 years old, 41.9 % female, 67.7 % Hispanic). Whereas the mean daily RHR did not demonstrate clear trends, the mean ACΔ-RHR for the cohort first reached 0 on POD 12 and stabilized on POD 14 (95 % confidence interval: POD [11,17]). Subgroup analysis showed that ACΔ-RHR stabilized on POD 9 for age of 3–10 years, POD 12 for age of 11–17 years, POD 12 for females and POD 10 for males.

Conclusions

The ACΔ-RHR is a promising clinical metric that could enhance post-surgical patient monitoring, such as for children following laparoscopic appendectomy for complicated appendicitis.

查看原文本刊更多论文

每日静息心率的自相关性：术后恢复的新指标。

目的静息心率（RHR）是反映个人生理状况的敏感指标。然而，由于基线 RHR 因年龄、性别、心血管健康状况和合并症等多种因素而存在很大差异，其在临床实践中的应用受到了限制。本研究旨在根据 RHR 的逐日变化--每日 RHR 的自相关性差异（ACΔ-RHR）--开发一种新型的、具有临床意义的指标，该指标适用于所有这些情况。我们在监测小儿阑尾切除术患者出院后恢复情况的背景下介绍了 ACΔ-RHR：方法：2019 年至 2022 年期间，在一家三级儿童医院接受腹腔镜阑尾切除术治疗复杂性阑尾炎的 3-17 岁儿童在术后 21 天（POD）内佩戴了 Fitbit。其中包括无并发症的患者，以描述正常恢复情况。以 POD 1-3 的 RHR 为基线，计算 POD 3-21 的每日 RHR 的自相关性（固定滞后 = 1）。然后，通过减去当天和前一天的自相关值来确定每天的 ACΔ-RHR 值。计算每日 RHR 的平均值和标准偏差，以估计哪个 POD 的 ACΔ-RHR 稳定在 0，这代表所有患者的总体 RHR 稳定和术后恢复情况。按年龄（3-10 岁 vs 11-17 岁）和性别进行了分组分析：共纳入 31 名患者（3-10 岁占 58.1%，女性占 41.9%，西班牙裔占 67.7%）。虽然平均日 RHR 没有显示出明显的趋势，但队列中的平均 ACΔ-RHR 在 POD 12 首次达到 0，并在 POD 14 趋于稳定（95 % 置信区间：POD [11,17]）。亚组分析显示，3-10 岁儿童的 ACΔ-RHR 在 POD 9 趋于稳定，11-17 岁儿童的 ACΔ-RHR 在 POD 12 趋于稳定，女性的 ACΔ-RHR 在 POD 12 趋于稳定，男性的 ACΔ-RHR 在 POD 10 趋于稳定：ACΔ-RHR是一种很有前途的临床指标，可加强对手术后患者的监测，例如对腹腔镜阑尾切除术后患复杂性阑尾炎的儿童。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Medical Informatics 医学-计算机：信息系统

CiteScore

8.90

自引率

4.10%

发文量

217

审稿时长

42 days

期刊介绍： International Journal of Medical Informatics provides an international medium for dissemination of original results and interpretative reviews concerning the field of medical informatics. The Journal emphasizes the evaluation of systems in healthcare settings. The scope of journal covers: Information systems, including national or international registration systems, hospital information systems, departmental and/or physician''s office systems, document handling systems, electronic medical record systems, standardization, systems integration etc.; Computer-aided medical decision support systems using heuristic, algorithmic and/or statistical methods as exemplified in decision theory, protocol development, artificial intelligence, etc. Educational computer based programs pertaining to medical informatics or medicine in general; Organizational, economic, social, clinical impact, ethical and cost-benefit aspects of IT applications in health care.