Treatment of women with generalized anxiety disorder during the postpartum period with paroxetine: A retrospective analysis of 11 years of clinical data.

IF 1.2 4区 医学 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Hasan Bakay, Sakir Gica, Faruk Uguz
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引用次数: 0

Abstract

We presented the results on the efficacy of paroxetine in postpartum women with generalized anxiety disorder (GAD) in current study. We included data on 33 patients to our study retrospectively. The patients were evaluated using the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders-Fourth Edition, the Clinical Global Impression-Improvement Scale, the Hamilton Depression rating Scale (HAM-D) and the Hamilton Rating Scale for Anxiety (HAM-A). The patients had significant improvement in both HAM-D and HAM-A scores following paroxetine treatment for 8 wk. The response and remission rates were 78.8 and 63.6%, respectively. Both rates were significantly higher the subgroup of patients without comorbid depression compared to patients with comorbid depression. Based on the findings of the present study, we suggest that paroxetine may be beneficial for in postpartum women with GAD.

用帕罗西汀治疗产后广泛性焦虑症妇女:对 11 年临床数据的回顾性分析。
我们在本次研究中介绍了帕罗西汀对产后广泛性焦虑症(GAD)妇女的疗效。我们以回顾性研究的方式纳入了 33 名患者的数据。我们使用《精神疾病诊断与统计手册》第四版的结构化临床访谈、临床总体印象改善量表、汉密尔顿抑郁评分量表(HAM-D)和汉密尔顿焦虑评分量表(HAM-A)对患者进行了评估。帕罗西汀治疗 8 周后,患者的 HAM-D 和 HAM-A 评分均有明显改善。应答率和缓解率分别为 78.8% 和 63.6%。与合并抑郁症患者相比,无合并抑郁症患者亚组的反应率和缓解率均明显较高。根据本研究的结果,我们认为帕罗西汀可能对患有严重抑郁症的产后妇女有益。
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来源期刊
CiteScore
3.30
自引率
7.10%
发文量
91
期刊介绍: Health Care for Women International is a critically acclaimed, international publication that provides a unique interdisciplinary approach to health care and related topics that concern women around the globe. Published twelve times a year, Health Care for Women International includes the newest research, theories, and issues in the fields of public health, social science, health care practice, and health care policy. Scholars and practitioners address topics such as cultural differences, alternative lifestyles, domestic violence, public health issues associated with the aging of the population, maternal morbidity and mortality, infectious diseases, and a host of other gender-based ethical issues. The editor also encourages discussion topics, inviting readers to comment on articles that focus on specific aspects of health issue for women.
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