Challenges of Cell Counting in Cell Therapy Products.

IF 3.2 4区医学 Q3 CELL & TISSUE ENGINEERING

Cell Transplantation Pub Date : 2024-01-01 DOI:10.1177/09636897241293628

Muyun Liu, Wanglong Chu, Tao Guo, Xiuping Zeng, Yan Shangguan, Fangtao He, Xiao Liang

引用次数: 0

Abstract

Cell counting is a common and fundamental cell measurement technique that plays a crucial role in the development and quality control of cell therapy products. However, accurate and reliable cell counting can be challenging owing to the complexity of cell preparations, diverse counting purposes, and various counting methods. This review summarizes the challenges encountered in cell counting for cell therapy products and provides strategies to improve the cell counting accuracy, thereby guiding the counting process and ensuring the quality of cell therapy products.

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细胞治疗产品中细胞计数的挑战。

细胞计数是一种常见的基本细胞测量技术，在细胞治疗产品的开发和质量控制中起着至关重要的作用。然而，由于细胞制备的复杂性、计数目的的多样性以及计数方法的多样性，准确可靠的细胞计数可能具有挑战性。本综述总结了细胞治疗产品的细胞计数过程中遇到的挑战，并提供了提高细胞计数准确性的策略，从而指导计数过程并确保细胞治疗产品的质量。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Cell Transplantation 生物-细胞与组织工程

CiteScore

6.00

自引率

3.00%

发文量

审稿时长

6 months

期刊介绍： Cell Transplantation, The Regenerative Medicine Journal is an open access, peer reviewed journal that is published 12 times annually. Cell Transplantation is a multi-disciplinary forum for publication of articles on cell transplantation and its applications to human diseases. Articles focus on a myriad of topics including the physiological, medical, pre-clinical, tissue engineering, stem cell, and device-oriented aspects of the nervous, endocrine, cardiovascular, and endothelial systems, as well as genetically engineered cells. Cell Transplantation also reports on relevant technological advances, clinical studies, and regulatory considerations related to the implantation of cells into the body in order to provide complete coverage of the field.