Outcomes among non-Western immigrant patients and Danish-born patients with acute myeloid Leukaemia: A Danish population-based cohort study.

IF 5.1 2区 医学 Q1 HEMATOLOGY
Daniel Tuyet Kristensen, Mikkel Runason Simonsen, Anne Stidsholt Roug, Claus Werenberg Marcher, Andreas Due Ørskov, Anne Louise Tøllbøll Sørensen, Tarec Christoffer El-Galaly, Joachim Baech
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引用次数: 0

Abstract

Non-Western immigrant patients (NWIPs) may be a vulnerable population when diagnosed and treated for acute myeloid leukaemia (AML). Here we report selected quality parameters related to diagnosis, treatment, and outcome of newly diagnosed AML among NWIPs (n = 119) and Danish-born patients (DBPs) (n = 4689). No adjusted differences were observed for time-to-diagnosis, time-to-treatment, treatment allocation, rates of complete remission, early death, allogeneic stem cell transplantation, and overall survival between NWIPs and DBPs. Among patients allocated for intensive chemotherapy, NWIPs were less likely to participate in clinical trials. The findings highlight equitable AML care but underscore the need to enhance NWIP participation in clinical trials.

非西方移民和丹麦出生的急性髓性白血病患者的预后:一项基于丹麦人口的队列研究。
非西方移民患者(NWIPs)在诊断和治疗急性髓性白血病(AML)时可能是一个易受伤害的群体。在此,我们报告了非西方移民患者(n = 119)和丹麦出生的患者(DBPs)(n = 4689)中与新诊断的急性髓性白血病的诊断、治疗和结果相关的部分质量参数。在诊断时间、治疗时间、治疗分配、完全缓解率、早期死亡率、同种异体干细胞移植率和总生存率方面,NWIPs和DBPs之间未发现调整后的差异。在被分配接受强化化疗的患者中,NWIPs参与临床试验的可能性较低。研究结果突显了急性髓细胞性白血病治疗的公平性,但也强调了加强NWIP参与临床试验的必要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
8.60
自引率
4.60%
发文量
565
审稿时长
1 months
期刊介绍: The British Journal of Haematology publishes original research papers in clinical, laboratory and experimental haematology. The Journal also features annotations, reviews, short reports, images in haematology and Letters to the Editor.
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