Antibiotic use in surgical infections at a tertiary teaching hospital in Ghana.

Ghana medical journal Pub Date : 2024-09-01 DOI:10.4314/gmj.v58i3.5

Josephine Mensah, Antoinette A Bediako-Bowan, Amos Amoako-Adusei, Franklin Acheampong, Mohammed Sheriff, Nii A Adu-Aryee

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Abstract

Objective: The study aimed to assess antibiotic prescribing and use patterns at the Department of Surgery, Korle Bu Teaching Hospital.

Design: A cross-sectional study design was employed in this study.

Setting: The study was conducted at the Department of Surgery, Korle Bu Teaching Hospital.

Participants: Forty-two prescribers out of 63 (67%) at the Department of Surgery responded to questionnaires. Over the study period, prescriptions and medical records of 1715 patients from the general surgery, neurosurgery, and urology units were reviewed.

Main outcome measures: Percentage of prescriptions with antibiotics, percentage of prescribers using guidelines for antibiotic prescriptions, and percentage using culture and sensitivity to inform antibiotic prescriptions.

Results: Of the 1715 prescriptions assessed, 75% (1294/1715) were from inpatients, and 45% (772/1715) included an antibiotic. Ciprofloxacin and metronidazole constituted 54% of antibiotic prescriptions from general surgery. Amoxicillin/clavulanic acid and ceftriaxone constituted 64.7% of antibiotic prescriptions from neurosurgery, and ceftriaxone and ciprofloxacin made up 37.7% of antibiotic prescriptions from urology. Microbiology testing was done for only 14.5% (9/62) of inpatients who received antibiotics for treatment. The choice of antibiotics was influenced mainly by doctors' previous experience (37/42, 88.1%).

Conclusion: Antibiotics are widely used. About half of all prescriptions had antibiotics, with ciprofloxacin and metronidazole constituting more than half of antibiotic prescriptions from general surgery. Doctors mainly based their antibiotic prescriptions on previous experience and occasionally on microbiological investigations.

Funding: None declared.

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加纳一家三级教学医院手术感染中的抗生素使用情况。

研究目的本研究旨在评估科勒布教学医院外科的抗生素处方和使用模式：设计：本研究采用横断面研究设计：研究地点：Korle Bu 教学医院外科部：外科部 63 名处方医生中有 42 名（67%）回答了调查问卷。在研究期间，审查了普通外科、神经外科和泌尿科 1715 名患者的处方和病历：主要结果指标：使用抗生素的处方比例、使用抗生素处方指南的处方医生比例、使用培养和药敏结果作为抗生素处方依据的处方医生比例：在评估的 1715 份处方中，75%（1294/1715）来自住院患者，45%（772/1715）包含抗生素。环丙沙星和甲硝唑占普外科抗生素处方的 54%。阿莫西林/克拉维酸和头孢曲松占神经外科抗生素处方的 64.7%，头孢曲松和环丙沙星占泌尿外科抗生素处方的 37.7%。在接受抗生素治疗的住院患者中，只有 14.5%（9/62）的患者进行了微生物检测。抗生素的选择主要受医生以往经验的影响（37/42，88.1%）：结论：抗生素被广泛使用。结论：抗生素的使用非常广泛，大约一半的处方中含有抗生素，其中环丙沙星和甲硝唑占普外科抗生素处方的一半以上。医生主要根据以往经验开具抗生素处方，偶尔也会根据微生物学检查结果开具处方：未声明。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Ghana medical journal

CiteScore

1.10

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0.00%

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