Biopharmaceutical pipeline funded by venture capital firms, 2014 to 2024.

Health affairs scholar Pub Date : 2024-10-04 eCollection Date: 2024-10-01 DOI:10.1093/haschl/qxae124
So-Yeon Kang, Mingqian Liu, Jeromie Ballreich, Ravi Gupta, Gerard Anderson
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Abstract

Venture capital (VC) firms fund biopharmaceutical research and development (R&D) while incurring substantial financial risk. VC firms seek to invest in clinical areas with the greatest potential for financial return. Using a combination of data for clinical trials and VC investment deals between January 2014 and March 2024, we found that approximately 75% of VC investments were allocated to clinical trials studying small-molecule drugs compared to biologics or gene therapies, without substantial changes over the study period. Most of VC firms' investment in biopharmaceutical R&D was concentrated in phase 1 and phase 2 clinical trials. This trend has increased in recent years, with phase 1 trials accounting for nearly half of total deals and capital investments in 2023. VC investments were concentrated in several therapeutic areas, including cancer.

2014 年至 2024 年风险投资公司资助的生物制药项目。
风险投资(VC)公司在为生物制药研发(R&D)提供资金的同时,也承担着巨大的财务风险。风险投资公司寻求投资于最具经济回报潜力的临床领域。利用 2014 年 1 月至 2024 年 3 月期间临床试验和风险投资交易的综合数据,我们发现,与生物制剂或基因疗法相比,大约 75% 的风险投资被分配给了研究小分子药物的临床试验,而且在研究期间没有发生重大变化。风险投资公司对生物制药研发的投资大多集中在 1 期和 2 期临床试验。这一趋势近年来有所上升,到 2023 年,1 期临床试验将占交易和资本投资总额的近一半。风险投资主要集中在几个治疗领域,包括癌症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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