Segmental Odontomaxillary Dysplasia: Systematic Review.

IF 3.2 Q2 PATHOLOGY
Alessandra Acioli Landim, Mariela Peralta-Mamani, Guilherme Acioli Landim, Ademir Franco, José Luiz Cintra Junqueira, Mariana Quirino Silveira Soares
{"title":"Segmental Odontomaxillary Dysplasia: Systematic Review.","authors":"Alessandra Acioli Landim, Mariela Peralta-Mamani, Guilherme Acioli Landim, Ademir Franco, José Luiz Cintra Junqueira, Mariana Quirino Silveira Soares","doi":"10.1007/s12105-024-01717-3","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>This PRISMA-guided and PROSPERO-registered systematic review aimed to summarise the current knowledge on the characteristics (clinical, radiographic, and histopathological) and treatment options for segmental odontomaxillary dysplasia (SOD).</p><p><strong>Methods: </strong>Descriptive studies, case series, and case reports were searched up to May 2024 in PubMed, Embase, Web of Science, SciELO, and the Cochrane Library databases. Statistical association analyses were performed on clinical variables, using chi-square tests.</p><p><strong>Results: </strong>The 35 included studies detailed 60 SOD cases in patients with a mean age of 12 ± 9.6 years. 11. Males were more frequently affected than females (62% or 1.6:1 ratio). Most cases involved the right maxilla (55%) and presented facial asymmetry and/or unilateral swelling (78%). Three cases involved both maxillae and mandible; Skin alterations were reported in 50% of the cases. Intraoral alterations such as alveolar process enlargement and gingival hyperplasia were also frequently observed (84% and 58%, respectively). All patients presented tooth alterations and 1st and/or 2nd upper premolars were absent in 80% of the cases. Dense bone and altered trabecular patterns were frequently observed in radiographs. Histopathological exams commonly showed dense trabecular bone and hyperplasic gingival tissue. Only 33 cases reported the SOD treatment, which ranged from follow-up without intervention up to surgery and orthodontics. No significant associations were found between sex and facial asymmetry or continuous lesion growth (p > 0.05). Additionally, no associations were found between intraoral alterations or symptoms and continuous lesion growth (p > 0.05).</p><p><strong>Conclusion: </strong>This review presents SOD epidemiological, clinical, radiographic and histopathological data. Evidence regarding treatment is scarce.</p>","PeriodicalId":47972,"journal":{"name":"Head & Neck Pathology","volume":"18 1","pages":"110"},"PeriodicalIF":3.2000,"publicationDate":"2024-10-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11496444/pdf/","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Head & Neck Pathology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1007/s12105-024-01717-3","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PATHOLOGY","Score":null,"Total":0}
引用次数: 0

Abstract

Purpose: This PRISMA-guided and PROSPERO-registered systematic review aimed to summarise the current knowledge on the characteristics (clinical, radiographic, and histopathological) and treatment options for segmental odontomaxillary dysplasia (SOD).

Methods: Descriptive studies, case series, and case reports were searched up to May 2024 in PubMed, Embase, Web of Science, SciELO, and the Cochrane Library databases. Statistical association analyses were performed on clinical variables, using chi-square tests.

Results: The 35 included studies detailed 60 SOD cases in patients with a mean age of 12 ± 9.6 years. 11. Males were more frequently affected than females (62% or 1.6:1 ratio). Most cases involved the right maxilla (55%) and presented facial asymmetry and/or unilateral swelling (78%). Three cases involved both maxillae and mandible; Skin alterations were reported in 50% of the cases. Intraoral alterations such as alveolar process enlargement and gingival hyperplasia were also frequently observed (84% and 58%, respectively). All patients presented tooth alterations and 1st and/or 2nd upper premolars were absent in 80% of the cases. Dense bone and altered trabecular patterns were frequently observed in radiographs. Histopathological exams commonly showed dense trabecular bone and hyperplasic gingival tissue. Only 33 cases reported the SOD treatment, which ranged from follow-up without intervention up to surgery and orthodontics. No significant associations were found between sex and facial asymmetry or continuous lesion growth (p > 0.05). Additionally, no associations were found between intraoral alterations or symptoms and continuous lesion growth (p > 0.05).

Conclusion: This review presents SOD epidemiological, clinical, radiographic and histopathological data. Evidence regarding treatment is scarce.

节段性牙颌发育不良:系统综述。
目的:这一PRISMA指导和PROSPERO注册的系统综述旨在总结节段性牙颌发育不良(SOD)的特征(临床、放射学和组织病理学)和治疗方案的现有知识:在 PubMed、Embase、Web of Science、SciELO 和 Cochrane Library 数据库中检索了截至 2024 年 5 月的描述性研究、系列病例和病例报告。采用卡方检验对临床变量进行统计关联分析:结果:纳入的 35 项研究详细记录了 60 例 SOD 病例,患者平均年龄为(12 ± 9.6)岁。11.男性患者多于女性患者(62%或1.6:1的比例)。大多数病例累及右上颌骨(55%),表现为面部不对称和/或单侧肿胀(78%)。有三个病例同时累及上颌骨和下颌骨;50%的病例有皮肤改变。牙槽突增大和牙龈增生等口腔内部改变也很常见(分别占 84% 和 58%)。所有患者的牙齿都有改变,80%的病例没有第一和/或第二上前磨牙。X光片经常观察到骨质致密和骨小梁形态改变。组织病理学检查常见致密的骨小梁和增生的牙龈组织。只有 33 个病例报告了 SOD 治疗情况,治疗范围从不加区分的随访到手术和正畸。性别与面部不对称或病变持续增长之间没有明显的关联(P > 0.05)。此外,口腔内改变或症状与病变的持续增长之间也没有关联(P > 0.05):本综述介绍了 SOD 的流行病学、临床、放射学和组织病理学数据。有关治疗的证据很少。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
求助全文
约1分钟内获得全文 求助全文
来源期刊
CiteScore
5.70
自引率
9.50%
发文量
99
期刊介绍: Head & Neck Pathology presents scholarly papers, reviews and symposia that cover the spectrum of human surgical pathology within the anatomic zones of the oral cavity, sinonasal tract, larynx, hypopharynx, salivary gland, ear and temporal bone, and neck. The journal publishes rapid developments in new diagnostic criteria, intraoperative consultation, immunohistochemical studies, molecular techniques, genetic analyses, diagnostic aids, experimental pathology, cytology, radiographic imaging, and application of uniform terminology to allow practitioners to continue to maintain and expand their knowledge in the subspecialty of head and neck pathology. Coverage of practical application to daily clinical practice is supported with proceedings and symposia from international societies and academies devoted to this field. Single-blind peer review The journal follows a single-blind review procedure, where the reviewers are aware of the names and affiliations of the authors, but the reviewer reports provided to authors are anonymous. Single-blind peer review is the traditional model of peer review that many reviewers are comfortable with, and it facilitates a dispassionate critique of a manuscript.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信