Deprescribing strategies in older patients with heart failure.

IF 3.2 3区医学 Q1 MEDICINE, GENERAL & INTERNAL

Internal and Emergency Medicine Pub Date : 2025-03-01 Epub Date: 2024-10-15 DOI:10.1007/s11739-024-03791-5

Gregorio Tersalvi, Vittorio Beltrani, Marco Peronti, Ludovico Furlan, Andrew Foy, Luigi Biasco

引用次数: 0

Abstract

Older patients with heart failure are particularly vulnerable due to a wide range of associated comorbidities, disability, and frailty. This population often receives multiple prescriptions, increasing the risk of adverse drug reactions, non-adherence, and drug interactions. Deprescribing, which involves reducing the number of medications to the lowest clinically reasonable limit, has the potential to decrease the risk of drug interactions and enhance patients' quality of life. Moreover, simplifying medication regimens may improve adherence to essential heart failure therapies. This scientific review aims to comprehensively examine deprescribing strategies in older patients with heart failure. It explores the rationale, challenges, benefits, and potential approaches to optimizing medication regimens in this vulnerable population. Furthermore, the review suggests a practical, step-by-step approach for performing deprescribing in older patients with heart failure.

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老年心力衰竭患者的减药策略。

老年心力衰竭患者由于伴有多种并发症、残疾和体弱，因此特别容易受到伤害。这类患者通常会接受多种处方，从而增加了药物不良反应、不依从性和药物相互作用的风险。去处方化是指将药物数量减少到临床合理的最低限度，有可能降低药物相互作用的风险并提高患者的生活质量。此外，简化用药方案还能提高患者对心衰基本疗法的依从性。本科学综述旨在全面研究老年心衰患者的减药策略。它探讨了在这一易感人群中优化用药方案的原理、挑战、益处和潜在方法。此外，该综述还提出了一种实用的、循序渐进的方法，用于对老年心力衰竭患者实施去处方化治疗。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Internal and Emergency Medicine 医学-医学：内科

CiteScore

7.20

自引率

4.30%

发文量

258

审稿时长

6-12 weeks

期刊介绍： Internal and Emergency Medicine (IEM) is an independent, international, English-language, peer-reviewed journal designed for internists and emergency physicians. IEM publishes a variety of manuscript types including Original investigations, Review articles, Letters to the Editor, Editorials and Commentaries. Occasionally IEM accepts unsolicited Reviews, Commentaries or Editorials. The journal is divided into three sections, i.e., Internal Medicine, Emergency Medicine and Clinical Evidence and Health Technology Assessment, with three separate editorial boards. In the Internal Medicine section, invited Case records and Physical examinations, devoted to underlining the role of a clinical approach in selected clinical cases, are also published. The Emergency Medicine section will include a Morbidity and Mortality Report and an Airway Forum concerning the management of difficult airway problems. As far as Critical Care is becoming an integral part of Emergency Medicine, a new sub-section will report the literature that concerns the interface not only for the care of the critical patient in the Emergency Department, but also in the Intensive Care Unit. Finally, in the Clinical Evidence and Health Technology Assessment section brief discussions of topics of evidence-based medicine (Cochrane’s corner) and Research updates are published. IEM encourages letters of rebuttal and criticism of published articles. Topics of interest include all subjects that relate to the science and practice of Internal and Emergency Medicine.