A LLM-Based Hybrid-Transformer Diagnosis System in Healthcare.

IF 6.7 2区 医学 Q1 COMPUTER SCIENCE, INFORMATION SYSTEMS
Dongyuan Wu, Liming Nie, Rao Asad Mumtaz, Kadambri Agarwal
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引用次数: 0

Abstract

The application of computer vision-powered large language models (LLMs) for medical image diagnosis has significantly advanced healthcare systems. Recent progress in developing symmetrical architectures has greatly impacted various medical imaging tasks. While CNNs or RNNs have demonstrated excellent performance, these architectures often face notable limitations of substantial losses in detailed information, such as requiring to capture global semantic information effectively and relying heavily on deep encoders and aggressive downsampling. This paper introduces a novel LLM-based Hybrid-Transformer Network (HybridTransNet) designed to encode tokenized Big Data patches with the transformer mechanism, which elegantly embeds multimodal data of varying sizes as token sequence inputs of LLMS. Subsequently, the network performs both inter-scale and intra-scale self-attention, processing data features through a transformer-based symmetric architecture with a refining module, which facilitates accurately recovering both local and global context information. Additionally, the output is refined using a novel fuzzy selector. Compared to other existing methods on two distinct datasets, the experimental findings and formal assessment demonstrate that our LLM-based HybridTransNet provides superior performance for brain tumor diagnosis in healthcare informatics.

基于 LLM 的混合变压器医疗诊断系统。
计算机视觉驱动的大型语言模型(LLM)在医学图像诊断中的应用极大地推动了医疗保健系统的发展。最近在开发对称架构方面取得的进展极大地影响了各种医学成像任务。虽然 CNNs 或 RNNs 表现出了卓越的性能,但这些架构往往面临着显著的局限性,如需要有效捕捉全局语义信息、严重依赖深度编码器和激进的降采样等,从而导致详细信息的大量损失。本文介绍了一种新颖的基于 LLM 的混合变换器网络(HybridTransNet),旨在利用变换器机制对标记化的大数据补丁进行编码,将不同大小的多模态数据优雅地嵌入 LLMS 的标记序列输入中。随后,该网络执行尺度间和尺度内的自我关注,通过基于转换器的对称架构和精炼模块处理数据特征,从而有助于准确恢复局部和全局上下文信息。此外,还使用了一种新颖的模糊选择器来完善输出。在两个不同的数据集上,与其他现有方法相比,实验结果和正式评估表明,我们基于 LLM 的 HybridTransNet 为医疗信息学中的脑肿瘤诊断提供了卓越的性能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
IEEE Journal of Biomedical and Health Informatics
IEEE Journal of Biomedical and Health Informatics COMPUTER SCIENCE, INFORMATION SYSTEMS-COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS
CiteScore
13.60
自引率
6.50%
发文量
1151
期刊介绍: IEEE Journal of Biomedical and Health Informatics publishes original papers presenting recent advances where information and communication technologies intersect with health, healthcare, life sciences, and biomedicine. Topics include acquisition, transmission, storage, retrieval, management, and analysis of biomedical and health information. The journal covers applications of information technologies in healthcare, patient monitoring, preventive care, early disease diagnosis, therapy discovery, and personalized treatment protocols. It explores electronic medical and health records, clinical information systems, decision support systems, medical and biological imaging informatics, wearable systems, body area/sensor networks, and more. Integration-related topics like interoperability, evidence-based medicine, and secure patient data are also addressed.
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