A randomized clinical trial testing digital mindset intervention for knee osteoarthritis pain and activity improvement

IF 12.4 1区医学 Q1 HEALTH CARE SCIENCES & SERVICES

NPJ Digital Medicine Pub Date : 2024-10-17 DOI:10.1038/s41746-024-01281-8

Melissa A. Boswell, Kris M. Evans, Disha Ghandwani, Trevor Hastie, Sean R. Zion, Paula L. Moya, Nicholas J. Giori, Jennifer L. Hicks, Alia J. Crum, Scott L. Delp

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Abstract

This randomized clinical trial evaluated the effectiveness of short, digital interventions in improving physical activity and pain for individuals with knee osteoarthritis. We compared a digital mindset intervention, focusing on adaptive mindsets (e.g., osteoarthritis is manageable), to a digital education intervention and a no-intervention group. 408 participants with knee osteoarthritis completed the study online in the US. The mindset intervention significantly improved mindsets compared to both other groups (P < 0.001) and increased physical activity levels more than the no-intervention group (mean = 28.6 points, P = 0.001), but pain reduction was not significant. The mindset group also showed significantly greater improvements in the perceived need for surgery, self-imposed physical limitations, fear of movement, and self-efficacy than the no-intervention and education groups. This trial demonstrates the effectiveness of brief digital interventions in educating about osteoarthritis and further highlights the additional benefits of improving mindsets to transform patients’ approach to disease management. The study was prospectively registered (ClinicalTrials.gov: NCT05698368, 2023-01-26).

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一项随机临床试验，测试针对膝关节骨性关节炎疼痛和活动改善的数字心态干预措施

这项随机临床试验评估了短期数字干预在改善膝关节骨性关节炎患者的体育锻炼和疼痛方面的效果。我们比较了数字心态干预（侧重于适应性心态，如骨关节炎是可以控制的）、数字教育干预和无干预组。408 名膝关节骨关节炎患者在美国完成了在线研究。与其他两组相比，心态干预组明显改善了心态（P <0.001），体育锻炼水平的提高幅度也高于未干预组（平均 = 28.6 分，P = 0.001），但疼痛减轻的幅度并不明显。与未干预组和教育组相比，心态组在手术需求感知、自我身体限制、运动恐惧和自我效能方面也有明显改善。这项试验证明了简短数字干预在骨关节炎教育方面的有效性，并进一步强调了改善心态以改变患者疾病管理方法的额外益处。该研究进行了前瞻性注册（ClinicalTrials.gov：NCT05698368，2023-01-26）。

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来源期刊

NPJ Digital Medicine Multiple-

CiteScore

25.10

自引率

3.30%

发文量

170

审稿时长

15 weeks

期刊介绍： npj Digital Medicine is an online open-access journal that focuses on publishing peer-reviewed research in the field of digital medicine. The journal covers various aspects of digital medicine, including the application and implementation of digital and mobile technologies in clinical settings, virtual healthcare, and the use of artificial intelligence and informatics. The primary goal of the journal is to support innovation and the advancement of healthcare through the integration of new digital and mobile technologies. When determining if a manuscript is suitable for publication, the journal considers four important criteria: novelty, clinical relevance, scientific rigor, and digital innovation.