Efficacy of in-person versus digital enhanced lifestyle interventions in adults with overweight and obesity

Obesity Pillars Pub Date : 2024-10-16 DOI:10.1016/j.obpill.2024.100133

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Abstract

Background

Lifestyle interventions (LIs) are the cornerstone for obesity management. The Mayo Clinic Diet (MCD) offers two approaches for LIs: the In-Person LI (IPLI) and the Digital Enhanced LI (DELI). The IPLI includes a 2-day in-person program with monthly follow-ups, whereas the DELI provides on-demand digital tools. The comparative efficacy of these approaches is currently unknown.

Methods

This retrospective study included two cohorts of adults with a body mass index (BMI) of ≥25 kg/m² and weight metrics at least 3 months after starting either the IPLI or DELI program. The primary endpoint was the total body weight loss percentage (TBWL%) at 6 months.

Results

The study included 133 participants in the IPLI cohort (mean age 46.3 years, 65.4 % female, BMI 36.4) and 9603 in the DELI cohort (mean age 60.1 years, 85.0 % female, BMI 33.1). The DELI group achieved superior TBWL% at 1, 3, and 6 months compared to the IPLI group (3.4 % vs. 1.5 %, 4.7 % vs. 2.4 %, 5.3 % vs. 2.9 %, respectively; p < 0.001). After adjusting for age, gender, and starting weight, the DELI group maintained a higher TBWL% (difference 2.0 %; 95 % CI [1.0, 3.0], p < 0.001) and a greater proportion of participants achieved >5 % TBWL at 6 months (OR 1.66; 95 % CI [1.08, 2.55], p < 0.023).

Conclusion

The DELI approach resulted in superior weight loss outcomes compared to the IPLI. Further research is needed to explore how digital tools can improve weight loss effectiveness.

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对超重和肥胖成人进行面对面干预与数字增强型生活方式干预的效果对比

背景生活方式干预（LIs）是肥胖管理的基石。梅奥诊所饮食中心（Mayo Clinic Diet，MCD）为生活方式干预提供了两种方法：面对面生活方式干预（IPLI）和数字增强生活方式干预（DELI）。IPLI 包括为期 2 天的面授课程和每月一次的随访，而 DELI 则提供按需使用的数字工具。这项回顾性研究包括两组体重指数（BMI）≥25 kg/m2，且在开始 IPLI 或 DELI 计划至少 3 个月后有体重指标的成年人。研究结果IPLI队列中有133名参与者（平均年龄46.3岁，65.4%为女性，体重指数36.4），DELI队列中有9603名参与者（平均年龄60.1岁，85.0%为女性，体重指数33.1）。与 IPLI 组相比，DELI 组在 1 个月、3 个月和 6 个月时的 TBWL% 更高（分别为 3.4% vs. 1.5%、4.7% vs. 2.4%、5.3% vs. 2.9%；P <0.001）。在对年龄、性别和起始体重进行调整后，DELI 组保持了更高的 TBWL%（差异为 2.0 %；95 % CI [1.0，3.0]，p < 0.001），并且有更大比例的参与者在 6 个月时达到了 >5 % 的 TBWL（OR 1.66；95 % CI [1.08，2.55]，p < 0.023）。需要进一步研究探索数字工具如何提高减肥效果。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Obesity Pillars

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