New Brønsted–Lowry acid Co(II) complexes: Synthesis, characterization, and investigation of electrochemical application for sensing of salbutamol

IF 2.4 3区化学 Q2 CHEMISTRY, INORGANIC & NUCLEAR

Polyhedron Pub Date : 2024-10-10 DOI:10.1016/j.poly.2024.117248

Bosena Dinber , Kidanemariam Teklay Hilawea , Endalamaw Yihune , Getasil Chanie , Melaku Metto , Mamaru Bitew , Getinet Tamiru Tigineh , Atakilt Abebe

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Abstract

In recent years, the employment of transition metal complexes for working electrode surface modification for sensor fabrication has become an area of research direction. Based on this, in this study, three Co(II) complexes: Co(phen)Cl₂ (CoC₁₂H₈N₂Cl₂) (C1), and Brønsted–Lowry acids Co(phen)(HTA)Cl (CoC₁₆H₁₃N₂O₆Cl)(C2), and Co(phen)(HTA)₂ (CoC₂₀H₁₈N₂O₁₂)(C3) were synthesized and characterized using various techniques such as UV–Vis, FT-IR, ICP OES, TGA, DTA, pXRD as well as electrolytic conductivity, and acid-base property analysis. C and C3 were found polycrystalline whose size falls within the nano range of 50 and 51 nm, respectively. The synthesis was intended to get materials for voltammetrically modifying glassy carbon electrodes for the determination of salbutamol. Salbutamol is a short-acting β₂ adrenergic receptor agonist that is applied for opening the medium and large airways in the lungs and eventually treats asthma among other problems. The electrochemical application of the synthesized materials was studied by fabricating through electropolymerization of C1, C2, and C3 on glassy carbon electrodes. The poly(C1)/GCE, poly(C2)/GCE, and poly(C3)/GCE) revealed effective surface area is 0.174 cm², 0.183 cm², and 0.281 cm², respectively, and electrochemical catalysis of the materials increased with the number of the tartrate. The Rct values are 5686, 242, 216, and 185 Ω cm², while the C_dl values are 9.93 × 10⁻⁸, 5.35 × 10⁻⁶, 1.25 × 10⁻⁵, and 2.72 × 10⁻⁵, for bare GCE, poly(C1)/GCE, poly(C2)/GCE and poly(C3)/GCE, respectively. Similarly, the rate of charge transfer (k°) increased significantly on the modified electrode compared to the bare GCE. Salbutamol demonstrated a single well-shaped irreversible oxidative peak at the modified electrodes in the ascending order of poly(C1)/GCE, poly(C2)/GCE, and poly(C3)/GCE when compared to a bare GCE.

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新的布氏-洛氏酸 Co(II) 复合物：合成、表征和用于沙丁胺醇传感的电化学应用研究

近年来，利用过渡金属配合物改性工作电极表面以制造传感器已成为一个研究方向。基于此，本研究采用了三种 Co（II）配合物：Co(phen)Cl2（CoC12H8N2Cl2）（C1），以及布氏-洛氏酸 Co(phen)(HTA)Cl（CoC16H13N2O6Cl）（C2）和 Co(phen)(HTA)2（CoC20H18N2O12）（C3）、傅立叶变换红外光谱、ICP OES、TGA、DTA、pXRD 以及电解电导率和酸碱性质分析等多种技术对它们进行了合成和表征。发现 C 和 C3 为多晶体，其尺寸分别为 50 纳米和 51 纳米。合成的目的是获得用于伏安法改性玻璃碳电极的材料，以测定沙丁胺醇。沙丁胺醇是一种短效 β2 肾上腺素能受体激动剂，可用于打开肺部的中气道和大气道，最终治疗哮喘等疾病。通过在玻璃碳电极上电聚合 C1、C2 和 C3，研究了合成材料的电化学应用。聚（C1）/GCE、聚（C2）/GCE 和聚（C3）/GCE 的有效表面积分别为 0.174 cm2、0.183 cm2 和 0.281 cm2，且材料的电化学催化作用随酒石酸盐数量的增加而增强。裸 GCE、poly(C1)/GCE、poly(C2)/GCE 和 poly(C3)/GCE 的 Rct 值分别为 5686、242、216 和 185 Ω cm2，Cdl 值分别为 9.93 × 10-8、5.35 × 10-6、1.25 × 10-5 和 2.72 × 10-5。同样，与裸 GCE 相比，修饰电极上的电荷转移速率（k°）显著增加。与裸 GCE 相比，沙丁胺醇在改性电极上显示出单个形状良好的不可逆氧化峰，由高到低依次为 poly(C1)/GCE、poly(C2)/GCE 和 poly(C3)/GCE。

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来源期刊

Polyhedron 化学-晶体学

CiteScore

4.90

自引率

7.70%

发文量

515

审稿时长

2 months

期刊介绍： Polyhedron publishes original, fundamental, experimental and theoretical work of the highest quality in all the major areas of inorganic chemistry. This includes synthetic chemistry, coordination chemistry, organometallic chemistry, bioinorganic chemistry, and solid-state and materials chemistry. Papers should be significant pieces of work, and all new compounds must be appropriately characterized. The inclusion of single-crystal X-ray structural data is strongly encouraged, but papers reporting only the X-ray structure determination of a single compound will usually not be considered. Papers on solid-state or materials chemistry will be expected to have a significant molecular chemistry component (such as the synthesis and characterization of the molecular precursors and/or a systematic study of the use of different precursors or reaction conditions) or demonstrate a cutting-edge application (for example inorganic materials for energy applications). Papers dealing only with stability constants are not considered.