Thermoresponsive and Supramolecular Polymers: Interesting Biomaterials for Drug Delivery

IF 3.2 3区生物学 Q2 BIOCHEMICAL RESEARCH METHODS

Biotechnology Journal Pub Date : 2024-10-09 DOI:10.1002/biot.202400379

Ahmad Darvishi, Mojtaba Ansari

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引用次数: 0

Abstract

How to use and deliver drugs to diseased and damaged areas has been one of the main concerns of pharmacologists and doctors for a long time. With the efforts of researchers, the advancement of technology, and the involvement of engineering in the health field, diverse and promising approaches have been studied and used to achieve this goal. A better understanding of biomaterials and the ability of production equipment led researchers to offer new drug delivery systems to the world. In recent decades, responsive polymers (exclusively to temperature and pH) and supramolecular polymers have received much attention due to their unique capabilities. Although this field of research still needs to be scrutinized and studied more, their recognition, examination, and use as drug delivery systems is a start for a promising future. This review study, focusing on temperature-responsive and supramolecular biomaterials and their application as drug delivery systems, deals with their structure, properties, and role in the noninvasive and effective delivery of medicinal agents.

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热致伸缩性和超分子聚合物：有趣的药物输送生物材料。

长期以来，如何使用药物并将药物输送到患病和受损部位一直是药理学家和医生关注的主要问题之一。随着研究人员的努力、技术的进步以及工程学在健康领域的应用，人们已经研究并使用了多种有前景的方法来实现这一目标。研究人员对生物材料有了更深入的了解，生产设备的能力也在不断提高，从而为世界提供了新的给药系统。近几十年来，响应性聚合物（专门针对温度和 pH 值）和超分子聚合物因其独特的性能而备受关注。尽管这一研究领域还需要更多的关注和研究，但对它们的认识、研究以及将其用作药物输送系统是一个充满希望的未来的开端。本综述研究以温度响应和超分子生物材料及其作为给药系统的应用为重点，论述了它们的结构、特性以及在非侵入性和有效给药方面的作用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Biotechnology Journal Biochemistry, Genetics and Molecular Biology-Molecular Medicine

CiteScore

8.90

自引率

2.10%

发文量

123

审稿时长

1.5 months

期刊介绍： Biotechnology Journal (2019 Journal Citation Reports: 3.543) is fully comprehensive in its scope and publishes strictly peer-reviewed papers covering novel aspects and methods in all areas of biotechnology. Some issues are devoted to a special topic, providing the latest information on the most crucial areas of research and technological advances. In addition to these special issues, the journal welcomes unsolicited submissions for primary research articles, such as Research Articles, Rapid Communications and Biotech Methods. BTJ also welcomes proposals of Review Articles - please send in a brief outline of the article and the senior author''s CV to the editorial office. BTJ promotes a special emphasis on: Systems Biotechnology Synthetic Biology and Metabolic Engineering Nanobiotechnology and Biomaterials Tissue engineering, Regenerative Medicine and Stem cells Gene Editing, Gene therapy and Immunotherapy Omics technologies Industrial Biotechnology, Biopharmaceuticals and Biocatalysis Bioprocess engineering and Downstream processing Plant Biotechnology Biosafety, Biotech Ethics, Science Communication Methods and Advances.