CBTRUS Statistical Report: Primary Brain and Other Central Nervous System Tumors Diagnosed in the United States in 2017-2021.

IF 16.4 1区 医学 Q1 CLINICAL NEUROLOGY
Mackenzie Price, Christine Ballard, Julia Benedetti, Corey Neff, Gino Cioffi, Kristin A Waite, Carol Kruchko, Jill S Barnholtz-Sloan, Quinn T Ostrom
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引用次数: 0

Abstract

The Central Brain Tumor Registry of the United States (CBTRUS), in collaboration with the Centers for Disease Control and Prevention and the National Cancer Institute, is the largest population-based registry focused exclusively on primary brain and other central nervous system (CNS) tumors in the United States (US) and represents the entire US population. This report contains the most up-to-date population-based data on primary brain tumors available and supersedes all previous reports in terms of completeness and accuracy. All rates are age-adjusted using the 2000 US standard population and presented per 100,000 population. Between 2017 and 2021, the average annual age-adjusted incidence rate (AAAIR) of all primary malignant and non-malignant brain and other CNS tumors was 25.34 per 100,000 population (malignant AAAIR=6.89 and non-malignant AAAIR=18.46). This overall rate was higher in females compared to males (28.77 versus 21.78 per 100,000) and non-Hispanic Black persons compared to persons who were non-Hispanic White (26.60 versus 25.72 per 100,000), non-Hispanic American Indian/Alaska Native (23.48 per 100,000), non-Hispanic Asian or Pacific Islander (19.86 per 100,000), and Hispanic persons of all races (22.37 per 100,000). Gliomas accounted for 22.9% of all tumors. The most commonly occurring malignant brain and other CNS histopathology was glioblastoma (13.9% of all tumors and 51.5% of all malignant tumors), and the most common predominantly non-malignant histopathology was meningioma (41.7% of all tumors and 56.8% of all non-malignant tumors). Glioblastomas were more common in males, and meningiomas were more common in females. In children and adolescents (ages 0-19 years), the incidence rate of all primary brain and other CNS tumors was 6.02 per 100,000 population. There were 87,053 deaths attributed to malignant brain and other CNS tumors between 2017 and 2021. This represents an average annual mortality rate of 4.41 per 100,000 population and an average of 17,411 deaths per year. The five-year relative survival rate following diagnosis of a malignant brain or other CNS tumor was 35.7%. For a non-malignant brain or other CNS tumor the five-year relative survival rate was 92.0%.

CBTRUS 统计报告:2017-2021年美国确诊的原发性脑肿瘤和其他中枢神经系统肿瘤。
美国中央脑肿瘤登记处 (CBTRUS) 与美国疾病控制和预防中心 (Centers for Disease Control and Prevention) 和美国国立癌症研究所 (National Cancer Institute) 合作,是专门针对美国原发性脑肿瘤和其他中枢神经系统 (CNS) 肿瘤的最大人群登记处,代表了整个美国人口。本报告包含最新的原发性脑肿瘤人群数据,在完整性和准确性方面超越了之前的所有报告。所有发病率均根据 2000 年美国标准人口进行了年龄调整,并以每 10 万人口为单位列出。2017 年至 2021 年期间,所有原发性恶性和非恶性脑肿瘤及其他中枢神经系统肿瘤的年均年龄调整发病率(AAAIR)为每 10 万人 25.34 例(恶性 AAAIR=6.89 例,非恶性 AAAIR=18.46 例)。与男性相比,女性的总患病率更高(28.77 对 21.78/100,000);与非西班牙裔白人相比,非西班牙裔黑人的总患病率更高(26.60 对 25.72/100,000);与非西班牙裔美国印第安人/阿拉斯加原住民相比,非西班牙裔美国印第安人/阿拉斯加原住民的总患病率更高(23.48/100,000);与非西班牙裔亚洲人或太平洋岛民相比,非西班牙裔亚洲人或太平洋岛民的总患病率更高(19.86/100,000);与所有种族的西班牙裔人相比,所有种族的西班牙裔人的总患病率更高(22.37/100,000)。胶质瘤占所有肿瘤的 22.9%。最常见的恶性脑部和其他中枢神经系统组织病理学是胶质母细胞瘤(占所有肿瘤的 13.9%,占所有恶性肿瘤的 51.5%),最常见的主要非恶性组织病理学是脑膜瘤(占所有肿瘤的 41.7%,占所有非恶性肿瘤的 56.8%)。胶质母细胞瘤在男性中更为常见,而脑膜瘤在女性中更为常见。在儿童和青少年(0-19 岁)中,所有原发性脑肿瘤和其他中枢神经系统肿瘤的发病率为每 10 万人 6.02 例。2017 年至 2021 年期间,共有 87053 人死于恶性脑肿瘤和其他中枢神经系统肿瘤。这意味着平均年死亡率为每 10 万人 4.41 例,平均每年死亡 17,411 例。恶性脑肿瘤或其他中枢神经系统肿瘤确诊后的五年相对生存率为 35.7%。非恶性脑肿瘤或其他中枢神经系统肿瘤的五年相对存活率为 92.0%。
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来源期刊
Neuro-oncology
Neuro-oncology 医学-临床神经学
CiteScore
27.20
自引率
6.30%
发文量
1434
审稿时长
3-8 weeks
期刊介绍: Neuro-Oncology, the official journal of the Society for Neuro-Oncology, has been published monthly since January 2010. Affiliated with the Japan Society for Neuro-Oncology and the European Association of Neuro-Oncology, it is a global leader in the field. The journal is committed to swiftly disseminating high-quality information across all areas of neuro-oncology. It features peer-reviewed articles, reviews, symposia on various topics, abstracts from annual meetings, and updates from neuro-oncology societies worldwide.
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