Jiaqi Sun , Chen Zhang , Linlin Xing , Longbo Zhang , Hongzhen Cai , Maozu Guo
{"title":"BAMRE: Joint extraction model of Chinese medical entities and relations based on Biaffine transformation with relation attention","authors":"Jiaqi Sun , Chen Zhang , Linlin Xing , Longbo Zhang , Hongzhen Cai , Maozu Guo","doi":"10.1016/j.jbi.2024.104733","DOIUrl":null,"url":null,"abstract":"<div><div>Electronic Health Records (EHRs) contain various valuable medical entities and their relationships. Although the extraction of biomedical relationships has achieved good results in the mining of electronic health records and the construction of biomedical knowledge bases, there are still some problems. There may be implied complex associations between entities and relationships in overlapping triplets, and ignoring these interactions may lead to a decrease in the accuracy of entity extraction. To address this issue, a joint extraction model for medical entity relations based on a relation attention mechanism is proposed. The relation extraction module identifies candidate relationships within a sentence. The attention mechanism based on these relationships assigns weights to contextual words in the sentence that are associated with different relationships. Additionally, it extracts the subject and object entities. Under a specific relationship, entity vector representations are utilized to construct a global entity matching matrix based on Biaffine transformations. This matrix is designed to enhance the semantic dependencies and relational representations between entities, enabling triplet extraction. This allows the two subtasks of named entity recognition and relation extraction to be interrelated, fully utilizing contextual information within the sentence, and effectively addresses the issue of overlapping triplets.</div><div>Experimental observations from the CMeIE Chinese medical relation extraction dataset and the Baidu2019 Chinese dataset confirm that our approach yields the superior <span><math><mrow><mi>F</mi><mn>1</mn></mrow></math></span> score across all cutting-edge baselines. Moreover, it offers substantial performance improvements in intricate situations involving diverse overlapping patterns, multitudes of triplets, and cross-sentence triplets.</div></div>","PeriodicalId":15263,"journal":{"name":"Journal of Biomedical Informatics","volume":"158 ","pages":"Article 104733"},"PeriodicalIF":4.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomedical Informatics","FirstCategoryId":"3","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1532046424001515","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"COMPUTER SCIENCE, INTERDISCIPLINARY APPLICATIONS","Score":null,"Total":0}
引用次数: 0
Abstract
Electronic Health Records (EHRs) contain various valuable medical entities and their relationships. Although the extraction of biomedical relationships has achieved good results in the mining of electronic health records and the construction of biomedical knowledge bases, there are still some problems. There may be implied complex associations between entities and relationships in overlapping triplets, and ignoring these interactions may lead to a decrease in the accuracy of entity extraction. To address this issue, a joint extraction model for medical entity relations based on a relation attention mechanism is proposed. The relation extraction module identifies candidate relationships within a sentence. The attention mechanism based on these relationships assigns weights to contextual words in the sentence that are associated with different relationships. Additionally, it extracts the subject and object entities. Under a specific relationship, entity vector representations are utilized to construct a global entity matching matrix based on Biaffine transformations. This matrix is designed to enhance the semantic dependencies and relational representations between entities, enabling triplet extraction. This allows the two subtasks of named entity recognition and relation extraction to be interrelated, fully utilizing contextual information within the sentence, and effectively addresses the issue of overlapping triplets.
Experimental observations from the CMeIE Chinese medical relation extraction dataset and the Baidu2019 Chinese dataset confirm that our approach yields the superior score across all cutting-edge baselines. Moreover, it offers substantial performance improvements in intricate situations involving diverse overlapping patterns, multitudes of triplets, and cross-sentence triplets.
期刊介绍:
The Journal of Biomedical Informatics reflects a commitment to high-quality original research papers, reviews, and commentaries in the area of biomedical informatics methodology. Although we publish articles motivated by applications in the biomedical sciences (for example, clinical medicine, health care, population health, and translational bioinformatics), the journal emphasizes reports of new methodologies and techniques that have general applicability and that form the basis for the evolving science of biomedical informatics. Articles on medical devices; evaluations of implemented systems (including clinical trials of information technologies); or papers that provide insight into a biological process, a specific disease, or treatment options would generally be more suitable for publication in other venues. Papers on applications of signal processing and image analysis are often more suitable for biomedical engineering journals or other informatics journals, although we do publish papers that emphasize the information management and knowledge representation/modeling issues that arise in the storage and use of biological signals and images. System descriptions are welcome if they illustrate and substantiate the underlying methodology that is the principal focus of the report and an effort is made to address the generalizability and/or range of application of that methodology. Note also that, given the international nature of JBI, papers that deal with specific languages other than English, or with country-specific health systems or approaches, are acceptable for JBI only if they offer generalizable lessons that are relevant to the broad JBI readership, regardless of their country, language, culture, or health system.