Economic impact of screening on postdiagnosis work productivity in Japanese women with breast cancer: a life-table modeling approach.

IF 4 3区医学 Q1 OBSTETRICS & GYNECOLOGY

Breast Cancer Pub Date : 2024-10-04 DOI:10.1007/s12282-024-01637-8

Yoshie Takatori-Shirakami, Mitsue Saito, Kazuhito Yokoyama

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引用次数: 0

Abstract

Background: In Japan, biennial mammography screening has been recommended for the early detection of breast cancer (BC) in women aged 40 years or above since 2004 by the Ministry of Health, Labor and Welfare. The purpose of this study is to estimate the economic impact of BC screening on work productivity, using a new measure called the productivity-adjusted life-year (PALY).

Methods: We used a dynamic life table modeling approach to estimate the work productivity of female patients aged 40-64 years diagnosed with BC in 2019 over the year of diagnosis and the subsequent 5 years. Changes in life-years, PALYs, and gross domestic product (GDP) were assessed by changing the screening detection rate from the current (34.2%) to an ideal (100%) percentage. Each input for modeling was obtained from the most recent public database available.

Results: BC patients were estimated to lose 1903 in life-years, 3596 in PALYs, and US$281 million in GDP at the current screening detection rate compared with the ideal detection rate. On the other hand, the following gains are expected when the current screening detection rate was increased to 40-80%; life-years gain; 168-1325, PALYs gain; 317-2503, GDP gain: US$25-196 million.

Conclusion: This study has used modeling to show that detecting BC without screening is associated with a lower work productivity and an economic and life-years loss. Encouraging BC screening may be beneficial to maintaining work productivity after diagnosis.

查看原文本刊更多论文

日本女性乳腺癌患者筛查对诊断后工作生产率的经济影响：生命表建模方法。

背景：自 2004 年起，日本厚生劳动省建议 40 岁及以上女性每两年进行一次乳房 X 线照相筛查，以早期发现乳腺癌（BC）。本研究的目的是采用一种名为 "生产率调整生命年"（PALY）的新方法，估算乳腺癌筛查对工作生产率的经济影响：我们采用动态生命表建模方法估算了 2019 年确诊 BC 的 40-64 岁女性患者在确诊当年及其后 5 年的工作生产率。通过将筛查检出率从目前的 34.2% 改为理想的 100% 来评估生命年、PALYs 和国内生产总值 (GDP) 的变化。建模的各项输入数据均来自现有的最新公共数据库：与理想的筛查率相比，在目前的筛查率下，估计 BC 患者将损失 1903 个生命年、3596 个 PALYs 和 2.81 亿美元的 GDP。另一方面，当目前的筛查检出率提高到 40%-80% 时，预计会有以下收益：生命年收益；168-1325 年，PALYs 收益；317-2503 年，GDP 收益：结论：本研究通过建模表明，不进行筛查而检测出 BC 会降低工作效率，造成经济和生命年损失。鼓励进行乳腺癌筛查可能有利于在确诊后保持工作效率。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Breast Cancer ONCOLOGY-OBSTETRICS & GYNECOLOGY

CiteScore

6.70

自引率

2.50%

发文量

105

审稿时长

6-12 weeks

期刊介绍： Breast Cancer, the official journal of the Japanese Breast Cancer Society, publishes articles that contribute to progress in the field, in basic or translational research and also in clinical research, seeking to develop a new focus and new perspectives for all who are concerned with breast cancer. The journal welcomes all original articles describing clinical and epidemiological studies and laboratory investigations regarding breast cancer and related diseases. The journal will consider five types of articles: editorials, review articles, original articles, case reports, and rapid communications. Although editorials and review articles will principally be solicited by the editors, they can also be submitted for peer review, as in the case of original articles. The journal provides the best of up-to-date information on breast cancer, presenting readers with high-impact, original work focusing on pivotal issues.