Repairing Dehiscence Defects at Implant Sites Using β-Tricalcium Phosphate/Calcium Sulfate Versus Xenograft Combined With Membrane: A Randomized Clinical Trial.

Aksornsan Pongsettakul, Narit Leepong, Srisurang Suttapreyasri
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Abstract

Guided bone regeneration (GBR) typically involves bone grafts and a membrane to enhance bone formation. Beta-tricalcium phosphate calcium sulfate (β-TCP/CS) is a novel material with self-hardening and tissue growth inhibition properties and can potentially replace the need for a membrane. This study compares β-tricalcium phosphate/calcium sulfate with deproteinized bovine bone mineral and a collagen membrane (DBBM/CM) to repair bone defects at implant sites over 6 months. Sixteen implant defects were divided into β-TCP/CS (n = 8) and DBBM/CM (n = 8). The results showed no significant differences in vertical and horizontal defect fill in millimeters between β-TCP/CS (2.87 ± 1.25 and 2.37 ± 1.06 mm, respectively) and DBBM/CM (3.5 ± 0.92 and 2.87 ± 1.12 mm, respectively). Buccal bone thickness (BT) alterations at the implant platform levels (BT0) were similar for both materials. However, β-TCP/CS exhibited greater bone alteration at the 2-mm level (BT2: -1.85 mm vs -0.47 mm) and 4-mm level (BT4: -1.79 mm vs 0.12 mm) apical to the implant platform compared to DBBM/CM. When assessing volume alteration, β-TCP/CS showed a significantly greater reduction at the platform to the 2 mm level (-61.98% vs -23.76%) than DBBM/CM. In conclusion, β-TCP/CS demonstrated promise for treating buccal bone defects around implants but exhibited higher graft reduction. This suggests that while β-tricalcium phosphate/calcium sulfate may offer clinical benefits, its potential for greater graft reduction should be considered. Further research and evaluation are warranted to fully understand the long-term implications of using β-TCP/CS in guided bone regeneration procedures.

使用 β-Tricalcium Phosphate/Calcium Sulfate 与 Xenograft Combined With Membrane 修复种植部位的开裂缺陷:随机临床试验。
引导骨再生(GBR)通常涉及骨移植和骨膜,以促进骨形成。β-磷酸三钙硫酸钙(β-TCP/CS)是一种新型材料,具有自硬和抑制组织生长的特性,有可能取代骨膜。本研究比较了β-磷酸三钙/硫酸钙与去蛋白牛骨矿物质和胶原膜(DBBM/CM)在六个月内修复种植部位骨缺损的效果。16 例种植体缺损分为 β-TCP/CS(8 例)和 DBBM/CM(8 例)。结果显示,β-TCP/CS(分别为 2.87±1.25 和 2.37±1.06 mm.)和 DBBM/CM (分别为 3.5±0.92 和 2.87±1.12 mm.)之间的垂直和水平缺损填充毫米数无明显差异。两种材料在种植体平台水平(BT0)的颊骨厚度(BT)变化相似。但是,与 DBBM/CM 相比,β-TCP/CS 在种植体平台顶端 2 毫米水平(BT2:-1.85 毫米 vs. -0.47 毫米)和 4 毫米水平(BT4:-1.79 毫米 vs. 0.12 毫米)的骨量变化更大。在评估体积改变时,β-TCP/CS 在平台至 2 mm 水平的减少量(-61.98% vs. -23.76%)明显高于 DBBM/CM。总之,β-TCP/CS 在治疗种植体周围的颊骨缺损方面表现出良好的前景,但其移植物减少率更高。这表明,β-TCP/CS 在提供临床益处的同时,也应考虑到其可能导致更高的移植物减少率。要充分了解在引导骨再生手术中使用 β-TCP/CS 的长期影响,还需要进一步的研究和评估。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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