{"title":"A review of the current trends in chronic wound and scar management.","authors":"Chantalle Crous, Judey Pretorius, Anél Petzer","doi":"10.25270/wmp.24010","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Aberrant tissue repair can result in the formation of chronic wounds and pathological scarring, which can severely impact a patient's quality of life. Due to their complexity, treatment of these conditions remains challenging.</p><p><strong>Purpose: </strong>This review article provides a brief overview of the various treatments with regards to application, possible mechanism(s) of action, new developments, and areas requiring further research.</p><p><strong>Methods: </strong>A literature review on the different therapies/products currently used for chronic wounds and pathological scars was conducted. Several databases-including PubMed, ScienceDirect, Web of Science, and Google Scholar-were searched to find relevant articles on this topic.</p><p><strong>Results: </strong>Numerous products and treatment options, including several promising new technologies, are currently available. These therapies/products aim to accelerate wound healing, reduce scarring, and ultimately reach the goal of scarless tissue regeneration.</p><p><strong>Conclusion: </strong>Currently, no gold standard therapy exists for chronic wounds and pathological scars. Existing treatments demonstrate varying levels of efficacy, and further research is required regarding their safety and molecular mechanism(s) of action.</p>","PeriodicalId":23741,"journal":{"name":"Wound management & prevention","volume":"70 3","pages":""},"PeriodicalIF":1.0000,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Wound management & prevention","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.25270/wmp.24010","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"DERMATOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Background: Aberrant tissue repair can result in the formation of chronic wounds and pathological scarring, which can severely impact a patient's quality of life. Due to their complexity, treatment of these conditions remains challenging.
Purpose: This review article provides a brief overview of the various treatments with regards to application, possible mechanism(s) of action, new developments, and areas requiring further research.
Methods: A literature review on the different therapies/products currently used for chronic wounds and pathological scars was conducted. Several databases-including PubMed, ScienceDirect, Web of Science, and Google Scholar-were searched to find relevant articles on this topic.
Results: Numerous products and treatment options, including several promising new technologies, are currently available. These therapies/products aim to accelerate wound healing, reduce scarring, and ultimately reach the goal of scarless tissue regeneration.
Conclusion: Currently, no gold standard therapy exists for chronic wounds and pathological scars. Existing treatments demonstrate varying levels of efficacy, and further research is required regarding their safety and molecular mechanism(s) of action.
背景：组织修复失常可导致慢性伤口和病理性瘢痕的形成，严重影响患者的生活质量。目的：这篇综述文章简要概述了各种治疗方法的应用、可能的作用机制、新进展以及需要进一步研究的领域：方法：对目前用于慢性伤口和病理性疤痕的各种疗法/产品进行了文献综述。搜索了多个数据库，包括 PubMed、ScienceDirect、Web of Science 和 Google Scholar，以查找与该主题相关的文章：结果：目前有许多产品和治疗方案，包括几种前景看好的新技术。这些疗法/产品旨在加速伤口愈合、减少疤痕，并最终实现无疤痕组织再生的目标：目前，慢性伤口和病理性疤痕还没有金标准疗法。结论：目前，慢性伤口和病理性疤痕的治疗还没有金标准，现有的治疗方法显示出不同程度的疗效，其安全性和分子作用机制还需要进一步研究。
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