Comparative Evaluation of the Antibiotic Resistance Profile of Staphylococcus aureus Isolated From Breeders and Livestock.

IF 2.6 3区医学 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

International Journal of Public Health Pub Date : 2024-09-18 eCollection Date: 2024-01-01 DOI:10.3389/ijph.2024.1607603

A C Ifediora, E Enya, C S Mbajiuka

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引用次数: 0

Abstract

Objectives: Animals are a potential source of Methicillin Resistant Staphylococcus aureus. This study evaluated the antibiotics susceptibility pattern of S. aureus isolates from breeders and livestock.

Methods: S. aureus strains were isolated from 180 livestock and 48 livestock farmers and identified using standard methods. Antibiotic susceptibility profiles and MRSA status were determined via disk diffusion susceptibility method.

Results: Among farm workers, 37.5% were colonized by S. aureus, with pig farm workers exhibiting the highest prevalence (56.2%), cattle herders (37.5%), and goat farm workers (18.7%). MRSA carriage among livestock isolates was 41.3%, while, six isolates from the poultry farm worker were MRSA, representing a carriage of 33.3%. Drug susceptibility profiles revealed differential patterns between isolates from breeders and animals. Gentamicin and levofloxacin demonstrated higher efficacy against farm worker isolates compared to animal isolates. Resistance to cefuroxime was higher among animal isolates (84.1%) as against the 66.7% for the breeders.

Conclusion: The identification of multidrug-resistant S. aureus strains underscores the risk posed to humans in contact with animals. These findings stress the importance of monitoring and managing MRSA transmission between animals and humans.

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种鸡和家畜分离出的金黄色葡萄球菌抗生素耐药性比较评估

目的：动物是耐甲氧西林金黄色葡萄球菌的潜在来源。本研究评估了从饲养者和牲畜中分离出的金黄色葡萄球菌的抗生素敏感性模式：方法：从 180 头牲畜和 48 个畜牧者身上分离出金葡菌菌株，并使用标准方法进行鉴定。通过磁盘扩散药敏法确定抗生素药敏谱和 MRSA 状态：结果：在农场工人中，37.5%的人感染了金黄色葡萄球菌，其中猪场工人感染率最高（56.2%），牛场工人感染率最高（37.5%），羊场工人感染率最高（18.7%）。家畜分离物中的 MRSA 携带率为 41.3%，而家禽养殖场工人的 6 个分离物为 MRSA，携带率为 33.3%。药物敏感性图谱显示了饲养员和动物分离物之间的不同模式。与动物分离物相比，庆大霉素和左氧氟沙星对农场工人分离物的疗效更高。动物分离物对头孢呋辛的耐药性较高（84.1%），而饲养员分离物对头孢呋辛的耐药性为 66.7%：耐多药金黄色葡萄球菌菌株的发现凸显了与动物接触的人类所面临的风险。这些发现强调了监测和管理 MRSA 在动物和人类之间传播的重要性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

International Journal of Public Health 医学-公共卫生、环境卫生与职业卫生

CiteScore

4.20

自引率

2.20%

发文量

269

审稿时长

12 months

期刊介绍： The International Journal of Public Health publishes scientific articles relevant to global public health, from different countries and cultures, and assembles them into issues that raise awareness and understanding of public health problems and solutions. The Journal welcomes submissions of original research, critical and relevant reviews, methodological papers and manuscripts that emphasize theoretical content. IJPH sometimes publishes commentaries and opinions. Special issues highlight key areas of current research. The Editorial Board''s mission is to provide a thoughtful forum for contemporary issues and challenges in global public health research and practice.