Quality of Life of Patients with Heart Failure Due to Myocardial Ischemia.

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Accounts of Chemical Research Pub Date : 2024-09-24 eCollection Date: 2024-09-01 DOI:10.31083/j.rcm2509342

Grażyna Bonek-Wytrych, Oskar Sierka, Magdalena Szynal, Józefa Dąbek

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Abstract

Background: Heart failure caused by myocardial ischemia is a common cause encountered in clinical practice. A significant problem in heart failure is its progressive, unfavorable course and the associated increased frequency of repeated hospitalizations, as well as a significant deterioration in the functioning of patients, leading to their inability to function independently and a significant decline in the quality of life. This study aimed to assess the quality of life of patients with heart failure due to myocardial ischemia, considering the left ventricular ejection fraction, the number of "diseased" coronary arteries, co-occurring diseases, and cardiovascular risk factors.

Methods: A total of 204 patients with decompensated heart failure due to chronic myocardial ischemia were included in this study and examined twice: A: on the first day of hospitalization; A': from 4 to 8 weeks. For the individual assessment of the quality of life, the WHOQOL-BREF (The World Health Organization Quality of Life - BREF) questionnaire was used.

Results: In the group of patients with heart failure in the decompensation stage a statistically significant positive relationship was observed between the number of comorbidities and the social domain (R(A) = 0.197; p(A) = 0.005), the number of diseased coronary arteries and the mental (R(A) = 0.184; p(A) = 0.184) and environmental (R(A) = 0.149; p(A) = 0.034) domains, left ventricular ejection fraction (LVEF%) and quality of life (R(A) = 0.235; p = 0.001) and satisfaction with health (R(A) = 0.235; p = 0.001) and somatic domain (R(A) = 0.194; p = 0.005). A similar result was observed among patients in the long-term follow-up. A statistically significant negative correlation was demonstrated in the mentioned group between the LVEF% value and the social domain (R(A) = -0.235; p = 0.001), as well as in the long-term follow-up (R(A') = -0.191, p = 0.026). The level of self-assessment of quality of life and satisfaction with health was statistically significantly higher among patients with heart failure in the long-term follow-up (3.20 ± 0.62) than in patients in the decompensation stage (1.98 ± 0.69).

Conclusions: The quality of life of the examined patients with heart failure caused by chronic myocardial ischemia was poor, although it improved to average in the long-term follow-up. It was determined by left ventricular ejection fraction, the number of "diseased" coronary arteries, comorbidities, and risk factors.

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心肌缺血所致心力衰竭患者的生活质量

背景：心肌缺血导致的心力衰竭是临床上常见的病因。心力衰竭的一个重要问题是其进行性的、不利的病程和相关的反复住院频率增加，以及患者功能的显著恶化，导致他们无法独立生活，生活质量明显下降。本研究旨在评估心肌缺血导致的心力衰竭患者的生活质量，同时考虑左心室射血分数、冠状动脉 "病变 "数量、并发疾病和心血管风险因素：本研究共纳入 204 名慢性心肌缺血导致的失代偿性心力衰竭患者，对他们进行了两次检查：A：住院第一天；A'：4 至 8 周。对个人生活质量的评估采用了世界卫生组织生活质量--BREF（WHOQOL-BREF）问卷：在处于失代偿期的心力衰竭患者组中，合并症数量与社会领域（R(A) = 0.197; p(A) = 0.005）、冠状动脉病变数量与精神领域（R(A) = 0.184; p(A) = 0.184）和环境（R(A) = 0.149; p(A) = 0.034）领域、左室射血分数（LVEF%）和生活质量（R(A) = 0.235; p = 0.001）以及健康满意度（R(A) = 0.235; p = 0.001）和躯体领域（R(A) = 0.194; p = 0.005）。在长期随访的患者中也观察到了类似的结果。在上述组别中，LVEF%值与社交领域（R(A) = -0.235；p = 0.001）以及长期随访（R(A' ) = -0.191，p = 0.026）之间存在统计学意义上的负相关。在长期随访中，心衰患者对生活质量和健康满意度的自我评估水平（3.20 ± 0.62）明显高于失代偿期患者（1.98 ± 0.69）：结论：慢性心肌缺血导致的心力衰竭患者的生活质量较差，但在长期随访中已改善至平均水平。生活质量取决于左心室射血分数、"病变 "冠状动脉数量、合并症和危险因素。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.