The effect of combined malnutrition and obesity on trauma and orthopaedic surgery outcomes.

IF 4.9 1区 医学 Q1 ORTHOPEDICS
Diego A Abelleyra Lastoria, Chigoziem Ogbolu, Olufemi Olatigbe, Rebecca Beni, Ahsan Iftikhar, Caroline B Hing
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引用次数: 0

Abstract

Aims: To determine whether obesity and malnutrition have a synergistic effect on outcomes from skeletal trauma or elective orthopaedic surgery.

Methods: Electronic databases including MEDLINE, Global Health, Embase, Web of Science, ScienceDirect, and PEDRo were searched up to 14 April 2024, as well as conference proceedings and the reference lists of included studies. Studies were appraised using tools according to study design, including the Oxford Levels of Evidence, the Institute of Health Economics case series quality appraisal checklist, and the CLARITY checklist for cohort studies. Studies were eligible if they reported the effects of combined malnutrition and obesity on outcomes from skeletal trauma or elective orthopaedic surgery.

Results: A total of eight studies (106,319 patients) were included. These carried moderate to high risk of bias. Combined obesity and malnutrition did not lead to worse outcomes in patients undergoing total shoulder arthroplasty or repair of proximal humeral fractures (two retrospective cohort studies). Three studies (two retrospective cohort studies, one case series) found that malnourishment and obesity had a synergistic effect and led to poor outcomes in total hip or knee arthroplasty, including longer length of stay and higher complication rates. One retrospective cohort study pertaining to posterior lumbar fusion found that malnourished obese patients had higher odds of developing surgical site infection and sepsis, as well as higher odds of requiring a revision procedure.

Conclusion: Combined malnutrition and obesity have a synergistic effect and lead to poor outcomes in lower limb procedures. Appropriate preoperative optimization and postoperative care are required to improve outcomes in this group of patients.

合并营养不良和肥胖对创伤和矫形手术结果的影响。
目的:确定肥胖和营养不良是否会对骨骼创伤或择期骨科手术的结果产生协同效应:检索了截至 2024 年 4 月 14 日的电子数据库,包括 MEDLINE、Global Health、Embase、Web of Science、ScienceDirect 和 PEDRo,以及会议论文集和纳入研究的参考文献目录。根据研究设计使用各种工具对研究进行评估,包括牛津证据等级、卫生经济研究所病例系列质量评估清单和队列研究的CLARITY清单。如果研究报告了合并营养不良和肥胖对骨骼创伤或择期矫形外科手术结果的影响,则符合条件:共纳入八项研究(106319 名患者)。这些研究存在中度至高度偏倚风险。在接受全肩关节置换术或肱骨近端骨折修复术的患者中,合并肥胖和营养不良并不会导致更差的治疗效果(两项回顾性队列研究)。三项研究(两项回顾性队列研究、一项病例系列研究)发现,营养不良和肥胖会产生协同效应,导致全髋关节或膝关节置换术的不良后果,包括住院时间更长、并发症发生率更高。一项关于腰椎后路融合术的回顾性队列研究发现,营养不良的肥胖患者发生手术部位感染和败血症的几率更高,需要进行翻修手术的几率也更高:结论:营养不良和肥胖会产生协同效应,导致下肢手术效果不佳。要改善这类患者的治疗效果,必须进行适当的术前优化和术后护理。
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来源期刊
Bone & Joint Journal
Bone & Joint Journal ORTHOPEDICS-SURGERY
CiteScore
9.40
自引率
10.90%
发文量
318
期刊介绍: We welcome original articles from any part of the world. The papers are assessed by members of the Editorial Board and our international panel of expert reviewers, then either accepted for publication or rejected by the Editor. We receive over 2000 submissions each year and accept about 250 for publication, many after revisions recommended by the reviewers, editors or statistical advisers. A decision usually takes between six and eight weeks. Each paper is assessed by two reviewers with a special interest in the subject covered by the paper, and also by members of the editorial team. Controversial papers will be discussed at a full meeting of the Editorial Board. Publication is between four and six months after acceptance.
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