Medication reconciliation enhances the accuracy of gastric emptying scintigraphy

IF 4.4 Q1 CHEMISTRY, INORGANIC & NUCLEAR

EJNMMI Radiopharmacy and Chemistry Pub Date : 2024-09-26 DOI:10.1186/s41181-024-00299-3

Vincent Nail, Alexandre Chapot, Oriane Nachar, Sophie Gabriel, Anaïs Moyon, David Taieb, Benjamin Guillet, Philippe Garrigue

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Abstract

Background

Gastroparesis (GP) is a prevalent sensorimotor disorder characterized by delayed gastric emptying without mechanical obstruction, posing significant diagnostic challenges. Gastric emptying scintigraphy (GES) is the gold standard for diagnosing GP. However, its accuracy can be compromised by many medications that affect gastric motility. This study evaluates the impact of medication reconciliation on the diagnostic accuracy of GES.

Results

A significant proportion of patients (75%) were on medications known to affect gastric motility. Recommendations for medication adjustments were communicated, with 30% non-adherence. Adjustments in GES interpretations were necessary for 20% of patients following comprehensive medication reviews. The involvement of radiopharmacists facilitated accurate diagnostic conclusions, underscoring the critical role of medication reconciliation in GES accuracy.

Conclusion

Medication reconciliation enhanced the accuracy of GES in diagnosing gastroparesis, emphasizing the need to integrate clinical pharmacy practices into nuclear medicine. This interdisciplinary approach not only improves diagnostic accuracy but also enhances patient safety, advocating for the adoption of such practices in the management of gastroparesis.

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药物调节可提高胃排空闪烁扫描的准确性

背景胃轻瘫（GP）是一种普遍存在的感觉运动障碍性疾病，其特征是胃排空延迟而无机械性梗阻，给诊断带来了巨大挑战。胃排空闪烁成像（GES）是诊断胃瘫的金标准。然而，许多影响胃动力的药物会影响其准确性。本研究评估了药物调节对胃排空闪烁扫描诊断准确性的影响。结果有相当一部分患者（75%）正在服用已知会影响胃动力的药物。药物调整的建议得到了传达，但有 30% 的患者没有遵照执行。20%的患者在接受全面药物检查后需要调整 GES 的解释。放射药剂师的参与促进了诊断结论的准确性，强调了药物调节对 GES 准确性的关键作用。这种跨学科的方法不仅提高了诊断的准确性，还增强了患者的安全性，提倡在胃痉挛的治疗中采用这种方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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