Liwei Zhu , Ting Liu , Zelong Duan, Ling Wang, Xuefan Qiu, Zhihan Sun, Chencan Li
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引用次数: 0
Abstract
The role of metal–organic frameworks (MOFs) in the field of enzyme-like materials is significant, and they have been successfully applied to various peroxidase-like studies involving catalytic oxidation of the substrate 3,3′,5,5′-tetramethylbenzidine (TMB). However, the limited chemical stability of MOFs in aqueous environments hampers their catalytic applications. To address this inherent drawback and enhance the peroxidase-like activity of MOFs, a method involving adenosine triphosphate (ATP) bonding was proposed. In this study, collaborative materials comprising cobalt MOFs (Co-MOFs) and ATP were utilized as model catalysts for TMB catalysis. The presence of ATP significantly improved the catalytic capability of Co-MOFs over a pH range from 3 to 9 and temperatures ranging from 25 to 60 °C. Notably, at pH 7 and 60 °C, the catalytic efficiency increased by approximately 100 times and an impressive enhancement rate of up to 4600% was achieved respectively. This peroxidase-like catalytic system offers a colorimetric detection assay that selectively detects L-cysteine with a limit of detection as low as 76.2 nM. Incorporating ATP into Co-MOFs presents a novel approach for utilizing MOFs in catalysis that is convenient, straightforward, and gentle.
期刊介绍:
Inorganica Chimica Acta is an established international forum for all aspects of advanced Inorganic Chemistry. Original papers of high scientific level and interest are published in the form of Articles and Reviews.
Topics covered include:
• chemistry of the main group elements and the d- and f-block metals, including the synthesis, characterization and reactivity of coordination, organometallic, biomimetic, supramolecular coordination compounds, including associated computational studies;
• synthesis, physico-chemical properties, applications of molecule-based nano-scaled clusters and nanomaterials designed using the principles of coordination chemistry, as well as coordination polymers (CPs), metal-organic frameworks (MOFs), metal-organic polyhedra (MPOs);
• reaction mechanisms and physico-chemical investigations computational studies of metalloenzymes and their models;
• applications of inorganic compounds, metallodrugs and molecule-based materials.
Papers composed primarily of structural reports will typically not be considered for publication.