Management of Vulvovaginal Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

IF 5.7 2区 医学 Q1 OBSTETRICS & GYNECOLOGY
Erin E Ross, Rachel C Knapp, Marcia A Ciccone, Warren L Garner, T Justin Gillenwater, Haig A Yenikomshian
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引用次数: 0

Abstract

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is an autoimmune process resulting in painful epidermal sloughing that can involve the vulva and vagina. Current guideline recommendations are based on expert opinion and may not reflect modern management of SJS/TEN in burn centers. We performed a retrospective chart review of 34 female patients treated for SJS/TEN at our burn center from 2015 to 2023. Cases frequently involved the vulva (83.3%) and vagina (56.0%), though pelvic examination often was limited. For eight patients with confirmed vulvovaginal lesions, there were no direct sequelae of SJS/TEN requiring intervention. In the modern era of SJS/TEN management in burn centers, interventions such as steroids may not be needed.

外阴史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症的处理方法。
史蒂文斯-约翰逊综合征和中毒性表皮坏死(SJS/TEN)是一种自身免疫过程,会导致表皮脱落,外阴和阴道也会受到感染。目前的指南建议基于专家意见,可能无法反映烧伤中心对 SJS/TEN 的现代管理。我们对 2015 年至 2023 年期间在烧伤中心接受 SJS/TEN 治疗的 34 名女性患者进行了回顾性病历审查。病例经常涉及外阴(83.3%)和阴道(56.0%),但盆腔检查往往有限。8例确诊为外阴阴道病变的患者没有出现需要干预的SJS/TEN直接后遗症。在烧伤中心进行SJS/TEN治疗的现代,可能不需要类固醇等干预措施。
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来源期刊
Obstetrics and gynecology
Obstetrics and gynecology 医学-妇产科学
CiteScore
11.10
自引率
4.20%
发文量
867
审稿时长
1 months
期刊介绍: "Obstetrics & Gynecology," affectionately known as "The Green Journal," is the official publication of the American College of Obstetricians and Gynecologists (ACOG). Since its inception in 1953, the journal has been dedicated to advancing the clinical practice of obstetrics and gynecology, as well as related fields. The journal's mission is to promote excellence in these areas by publishing a diverse range of articles that cover translational and clinical topics. "Obstetrics & Gynecology" provides a platform for the dissemination of evidence-based research, clinical guidelines, and expert opinions that are essential for the continuous improvement of women's health care. The journal's content is designed to inform and educate obstetricians, gynecologists, and other healthcare professionals, ensuring that they stay abreast of the latest developments and best practices in their field.
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