Management of Vulvovaginal Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis.

IF 8.3 2区 材料科学 Q1 MATERIALS SCIENCE, MULTIDISCIPLINARY
Erin E Ross, Rachel C Knapp, Marcia A Ciccone, Warren L Garner, T Justin Gillenwater, Haig A Yenikomshian
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引用次数: 0

Abstract

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is an autoimmune process resulting in painful epidermal sloughing that can involve the vulva and vagina. Current guideline recommendations are based on expert opinion and may not reflect modern management of SJS/TEN in burn centers. We performed a retrospective chart review of 34 female patients treated for SJS/TEN at our burn center from 2015 to 2023. Cases frequently involved the vulva (83.3%) and vagina (56.0%), though pelvic examination often was limited. For eight patients with confirmed vulvovaginal lesions, there were no direct sequelae of SJS/TEN requiring intervention. In the modern era of SJS/TEN management in burn centers, interventions such as steroids may not be needed.

外阴史蒂文斯-约翰逊综合征和中毒性表皮坏死松解症的处理方法。
史蒂文斯-约翰逊综合征和中毒性表皮坏死(SJS/TEN)是一种自身免疫过程,会导致表皮脱落,外阴和阴道也会受到感染。目前的指南建议基于专家意见,可能无法反映烧伤中心对 SJS/TEN 的现代管理。我们对 2015 年至 2023 年期间在烧伤中心接受 SJS/TEN 治疗的 34 名女性患者进行了回顾性病历审查。病例经常涉及外阴(83.3%)和阴道(56.0%),但盆腔检查往往有限。8例确诊为外阴阴道病变的患者没有出现需要干预的SJS/TEN直接后遗症。在烧伤中心进行SJS/TEN治疗的现代,可能不需要类固醇等干预措施。
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来源期刊
ACS Applied Materials & Interfaces
ACS Applied Materials & Interfaces 工程技术-材料科学:综合
CiteScore
16.00
自引率
6.30%
发文量
4978
审稿时长
1.8 months
期刊介绍: ACS Applied Materials & Interfaces is a leading interdisciplinary journal that brings together chemists, engineers, physicists, and biologists to explore the development and utilization of newly-discovered materials and interfacial processes for specific applications. Our journal has experienced remarkable growth since its establishment in 2009, both in terms of the number of articles published and the impact of the research showcased. We are proud to foster a truly global community, with the majority of published articles originating from outside the United States, reflecting the rapid growth of applied research worldwide.
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