High-Intensity Focused Ultrasound Ablation Combined With Hysteroscopy for the Treatment of Uterine Arteriovenous Fistula Associated With Retained Products of Conception: A Prospective Cohort Study.

IF 3.5 2区 医学 Q1 OBSTETRICS & GYNECOLOGY
Journal of minimally invasive gynecology Pub Date : 2025-01-01 Epub Date: 2024-09-12 DOI:10.1016/j.jmig.2024.09.010
Lili Xu, Haining Chen, Yanju Xiao, Zhifeng Jiang, Jing Zhang, Yanming Jiang, Dan Ling
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引用次数: 0

Abstract

Study objective: To evaluate the efficacy of combining high-intensity focused ultrasound (HIFU) ablation with hysteroscopic removal of retained products of conception in the presence of a uterine arteriovenous fistula (UAVF).

Design: Prospective cohort study SETTING: Tertiary hospital.

Patients: Seventeen patients with UAVF and retained products of conception.

Interventions: HIFU ablation combined with hysteroscopic removal of retained products of conception.

Measurements and main results: All patients presented with irregular vaginal bleeding following pregnancy termination and were not responsive to medical treatment. Patients were confirmed to have a UAVF along with concurrent intrauterine residue using three-dimensional color Doppler ultrasonography, uterine angiography, or pelvic-enhanced magnetic resonance imaging; and demonstrated a poor response to medical treatment. Under real-time ultrasound guidance, HIFU was used to ablate the arteriovenous malformation region. Patients underwent hysteroscopic removal of retained products of conception; the removed tissue was subjected to pathological examination. All patients underwent monthly uterine color Doppler ultrasound examinations and menstrual status follow-up within 3 months postoperatively and showed normal menstrual recovery without signs of arteriovenous malformations on ultrasonography. Pathological examination of the tissues removed during hysteroscopic clearance revealed characteristics consistent with pregnancy, with abnormal blood vessels in some tissues. All patients experienced normal menstrual recovery postoperatively, without intrauterine adhesions.

Conclusion: Combining HIFU ablation with postoperative hysteroscopic surgery effectively treats pregnancy-related UAVF with minimal complications and preserves fertility, it offers an additional treatment option for patients wanting future fertility.

高强度聚焦超声消融联合宫腔镜治疗与受孕产物滞留相关的子宫动静脉瘘:一项前瞻性队列研究。
目的评估在存在子宫动静脉瘘(UAVF)的情况下,将高强度聚焦超声(HIFU)消融术与宫腔镜清除受孕产物相结合的疗效:前瞻性队列研究:参与者干预措施: HIFU消融术联合子宫动静脉瘘治疗:结果:所有患者均在终止妊娠后出现不规则阴道出血,且对药物治疗无反应。通过三维彩色多普勒超声波检查、子宫血管造影术或盆腔增强磁共振成像检查,患者被证实患有UAVF,同时伴有宫内残留物;且对药物治疗反应不佳。在实时超声引导下,采用 HIFU 对动静脉畸形区域进行消融。患者在宫腔镜下取出滞留的受孕产物,并对取出的组织进行病理检查。所有患者均在术后3个月内接受了每月一次的子宫彩色多普勒超声检查和月经状况随访,超声检查结果显示月经恢复正常,无动静脉畸形迹象。宫腔镜清宫术中取出的组织病理检查显示与妊娠特征一致,部分组织中存在异常血管。所有患者术后月经恢复正常,无宫腔内粘连:结论:将 HIFU 消融术与术后宫腔镜手术相结合,可有效治疗与妊娠相关的子宫内膜异位症,且并发症极少,还能保留生育能力;为希望今后生育的患者提供了一种额外的治疗选择。
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来源期刊
CiteScore
5.00
自引率
7.30%
发文量
272
审稿时长
37 days
期刊介绍: The Journal of Minimally Invasive Gynecology, formerly titled The Journal of the American Association of Gynecologic Laparoscopists, is an international clinical forum for the exchange and dissemination of ideas, findings and techniques relevant to gynecologic endoscopy and other minimally invasive procedures. The Journal, which presents research, clinical opinions and case reports from the brightest minds in gynecologic surgery, is an authoritative source informing practicing physicians of the latest, cutting-edge developments occurring in this emerging field.
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